Xiang, Y. Z.; Chen, S.; Wang, X. Preparation and properties of four-arm polycaprolactone scaffolds for soft tissue engineering by photo-click chemical cross-linking. Acta Polymerica Sinica, 2025, 56(7), 1159-1169
a new DLP-compatible photosensitive resin based on the alkyne-capped four-arm polycaprolactone (4sPCL)-pentaerythritol tetrakis(mercaptoacetic acid) ester (PETMA) photoclick chemical cross-linking system was developed in response to the problems of the high rigidity of the traditional polycaprolactone (PCL) materials and the limited variety of photosensitive resins for digital light processing (DLP) technology. The light-curing uniformity
mechanical properties and thermal behavior of the scaffolds were systematically investigated by regulat
ing the molecular weight and addition concentration of 4sPCL. The experiments showed that when
M
n
=5000 g/mol and 10 wt% of 4sPCL were used
the prepared scaffolds possessed soft-tissue-matched compressive strength ((86.1±8.1) kPa)
fast light-curing properties (20-25 s) and excellent shape recovery. This study provides an innovative solution for the construction of soft tissue engineering scaffolds with precise structural modulation and biomimetic mechanical properties.
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