

浏览全部资源
扫码关注微信
1.浙江大学化学工程与生物工程学院 浙江省全省智能生物材料重点实验室 杭州 310027
2.浙江大学宁波国际科创中心 宁波市烯烃聚合物分子设计与智能制造重点实验室 宁波 315100
Received:26 April 2026,
Accepted:26 May 2026,
Online First:10 July 2026,
移动端阅览
井倩雯, 黄友佳, 杨晨, 许锋, 陈狄, 赵骞. 水凝胶表面结构与性能的图案化调控及应用. 高分子学报, doi: 10.11777/j.issn1000-3304.2026.26139.
Jing, Q. W.; Huang, Y. J.; Yang, C.; Xu, F.; Chen, D.; Zhao, Q. Surface patterning of hydrogels and their applications. Acta Polymerica Sinica, doi: 10.11777/j.issn1000-3304.2026.26139.
井倩雯, 黄友佳, 杨晨, 许锋, 陈狄, 赵骞. 水凝胶表面结构与性能的图案化调控及应用. 高分子学报, doi: 10.11777/j.issn1000-3304.2026.26139. DOI: CSTR: 32057.14.GFZXB.2026.7647.
Jing, Q. W.; Huang, Y. J.; Yang, C.; Xu, F.; Chen, D.; Zhao, Q. Surface patterning of hydrogels and their applications. Acta Polymerica Sinica, doi: 10.11777/j.issn1000-3304.2026.26139. DOI: CSTR: 32057.14.GFZXB.2026.7647.
水凝胶因与生物组织相似的力学特征与丰富的刺激响应性,已在航空航天、生物医药以及柔性电子等方面展现出良好的应用前景,并在许多关键领域已有应用. 其表面作为应用中与其他物体或装置产生相互作用的区域,同功能的实现息息相关. 然而,传统水凝胶一般质地均匀,且表面无特殊微纳结构,难以满足复杂场景对材料表面特性的精细需求,制约了材料应用的拓展. 对此,近期发展了一系列基于不同化学或物理过程的方法,实现了水凝胶表面性能的精准调控,包括浸润性、黏附性以及光学性能等,以满足不同场景的差异化需求. 本文聚焦水凝胶表面性能的图案化调控,围绕特性-策略-应用3个维度,对近期相关领域的研究成果进行综述,并提出所面临的机遇与挑战. 特别地,本文着重论述了基于光化学过程实现水凝胶表面性能调控的方法,为相关研究提供良好的借鉴.
Owing to the tissue-like mechanical properties and environmental responsiveness
hydrogels exhibit great potential in diverse fields
including aerospace
biomedicine
and flexible electron
ics. Their surfaces are the regions interacted with other objects during utilizations
which are essential to the realization of functions. However
conventional homogeneous hydrogels are hard to meet precise requirements of surface characteristics in complex scenarios
limiting the expansion of their applications. To address this
recent studies have focused on patterning the surface properties of hydrogels
such as wettability
adhesion
and optical properties. Many strategies are developed enabled by different chemical or physical procedures
thus meeting the differential demands of scenarios. This review focuses on patterning of hydrogel surface properties
summarizing recent achievements in this field. Furthermore
it provides a perspective about the latest opportunities and challenges according to our research. Especially
we emphasize the approach and merits of patterning hydrogel surfaces
via
photochemistry to give valuable references for future works.
Yuk H. ; Wu J. J. ; Zhao X. H. Hydrogel interfaces for merging humans and machines . Nat. Rev. Mater. , 2022 , 7 ( 12 ), 935 - 952 . doi: 10.1038/s41578-022-00483-4 http://dx.doi.org/10.1038/s41578-022-00483-4
Duan S. D. ; Hua M. T. ; Zhang C. W. ; Hong W. ; Yan Y. C. ; Jazzar A. ; Chen C. ; Shi P. J. ; Si M. Q. ; Wu D. ; Lin Z. S. ; He P. ; Du Y. J. ; He X. M. Noncovalent aggregation for diverse properties in hydrogels: a comprehensive review . Chem. Rev. , 2025 , 125 ( 16 ), 7918 - 7964 . doi: 10.1021/acs.chemrev.5c00069 http://dx.doi.org/10.1021/acs.chemrev.5c00069
Ni C. J. ; Chen D. ; Yin Y. ; Wen X. ; Chen X. L. ; Yang C. ; Chen G. C. ; Sun Z. ; Wen J. H. ; Jiao Y. R. ; Wang C. Y. ; Wang N. ; Kong X. X. ; Deng S. H. ; Shen Y. Q. ; Xiao R. ; Jin X. M. ; Li J. ; Kong X. Q. ; Zhao Q. ; Xie T. Shape memory polymer with programmable recovery onset . Nature , 2023 , 622 ( 7984 ), 748 - 753 . doi: 10.1038/s41586-023-06520-8 http://dx.doi.org/10.1038/s41586-023-06520-8
Hu Y. N. ; Wei H. ; Zhang H. ; Cheng H. ; Xu D. Y. ; Wang H. ; Zhang Z. Y. ; Zhang B. ; Liu Y. X. ; Wang Y. S. ; Zhang C. ; Li J. L. ; Zhao Y. J. ; Chai R. J. Magnetic nanochain-induced anisotropic nerve assembly for spinal cord injury repair . Chem. Eng. J. , 2024 , 501 , 157681 . doi: 10.1016/j.cej.2024.157681 http://dx.doi.org/10.1016/j.cej.2024.157681
Wang Y. ; Wang J. X. ; University B. ; Lee C. ; Li Y. H. Low-impedance and degradable soft dual-mode hydrogel sensor for real-time strain and bioelectric signal acquisition . ACS Appl. Electron. Mater. , 2025 , 7 ( 21 ), 9678 - 9691 . doi: 10.1021/acsaelm.5c01031 http://dx.doi.org/10.1021/acsaelm.5c01031
Cai Y. M. ; Wang C. X. ; Yang M. ; Li Y. P. ; Zhang F. L. ; Wang S. T. Bioinspired programmable biaxial rolling gel sheets for complex 3D morphing . Adv. Mater. , 2026 , 38 ( 13 ), e 19226 . doi: 10.1002/adma.202519226 http://dx.doi.org/10.1002/adma.202519226
Munoz-Robles B. G. ; Kopyeva I. ; DeForest C. A. Surface patterning of hydrogel biomaterials to probe and direct cell-matrix interactions . Adv. Mater. Interfaces , 2020 , 7 ( 21 ), 2001198 . doi: 10.1002/admi.202070116 http://dx.doi.org/10.1002/admi.202070116
Bai H. ; Zhang L. ; Gu D. Micrometer-sized spherulites as building blocks for lotus leaf-like superhydrophobic coatings . Appl. Surf. Sci. , 2018 , 459 , 54 - 62 . doi: 10.1016/j.apsusc.2018.07.183 http://dx.doi.org/10.1016/j.apsusc.2018.07.183
Dong X. X. ; Zhang R. ; Tian Y. ; Ramos M. A. ; Hu T. S. ; Wang Z. H. ; Zhao H. ; Zhang L. P. ; Wan Y. Y. ; Xia Z. H. ; Xu Q. Functionally graded gecko setae and the biomimics with robust adhesion and durability . ACS Appl. Polym. Mater. , 2020 , 2 ( 7 ), 2658 - 2666 . doi: 10.1021/acsapm.0c00282 http://dx.doi.org/10.1021/acsapm.0c00282
Zhao H. B. ; Park S. J. ; Solomon B. R. ; Kim S. ; Soto D. ; Paxson A. T. ; Varanasi K. K. ; Hart A. J. Synthetic butterfly scale surfaces with compliance-tailored anisotropic drop adhesion . Adv. Mater. , 2019 , 31 ( 14 ), 1807686 . doi: 10.1002/adma.201807686 http://dx.doi.org/10.1002/adma.201807686
Xu X. B. ; Liu J. W. ; Weng J. H. ; Wen W. ; Yu D. F. ; Wen J. X. ; Wu X. Underwater antiadhesion hydrogel coatings with spontaneous segment orientation . Chem. Eng. Sci. , 2025 , 301 , 120700 . doi: 10.1016/j.ces.2024.120700 http://dx.doi.org/10.1016/j.ces.2024.120700
Gao H. X. ; Wan X. Z. ; Yang Y. M. ; Lu J. W. ; Zhu Q. L. ; Xu L. P. ; Wang S. T. Leaf-inspired patterned organohydrogel surface for ultrawide time-range open biosensing . Adv. Sci. , 2023 , 10 ( 11 ), 2207702 . doi: 10.1002/advs.202207702 http://dx.doi.org/10.1002/advs.202207702
陈帅 , 严淑珍 , 印杰 , 姜学松 . 高分子材料图案记忆表面 . 高分子学报 , 2021 , 52 ( 10 ), 1245 - 1261 . doi: 10.11777/j.issn1000-3304.2021.21072 http://dx.doi.org/10.11777/j.issn1000-3304.2021.21072
Yu Z. Q. ; Gu Y. Q. ; Ren Y. ; Sun Y. F. ; Wu D. H. ; Mou J. G. ; Wu Z. X. ; Xu Y. The impact of intermolecular interactions on the actuation performance of stimuli-responsive hydrogels . Chem. Eng. J. , 2025 , 526 , 170724 . doi: 10.1016/j.cej.2025.170724 http://dx.doi.org/10.1016/j.cej.2025.170724
Zhu B. ; Wu J. Y. ; Liu D. S. ; Yan Y. K. ; Yang X. X. ; Wang Y. X. ; Bai C. C. ; Hu D. L. ; Zhang Z. X. ; Jiang P. ; Wang X. L. Sculpting mechanical properties of hydrogels by patterning seamlessly interlocked stiff skeleton . Adv. Funct. Mater. , 2025 , 35 ( 12 ), 2417477 . doi: 10.1002/adfm.202417477 http://dx.doi.org/10.1002/adfm.202417477
Liu H. R. ; Liu D. ; Yang J. C. ; Gao H. F. ; Wu Y. C. Flexible electronics based on organic semiconductors: from patterned assembly to integrated applications . Small , 2023 , 19 ( 11 ), 2206938 . doi: 10.1002/smll.202206938 http://dx.doi.org/10.1002/smll.202206938
Han X. ; Lin X. J. ; Sun Y. F. ; Huang L. L. ; Huo F. W. ; Xie R. J. Advancements in flexible electronics fabrication: film formation, patterning, and interface optimization for cutting-edge healthcare monitoring devices . ACS Appl. Mater. Interfaces , 2024 , acsami . 4 c 11976 . doi: 10.1021/acsami.4c11976 http://dx.doi.org/10.1021/acsami.4c11976
Xu C. ; Zhao Z. C. ; Zhang L. ; Zhou X. L. ; Wang Z. G. ; Liu Q. P. ; Ren L. Q. Electrode-integrated 4D printing enables hydrogel shape morphing: a critical breakthrough for bio-inspired actuators . Chem. Eng. J. , 2025 , 519 , 165268 . doi: 10.1016/j.cej.2025.165268 http://dx.doi.org/10.1016/j.cej.2025.165268
李景辉 , 王雷 , 仝佳琪 , 郑成林 , 杨文杰 , 王京霞 , 江雷 . 聚合物蓝相液晶的图案化研究进展 . 高分子学报 , 2025 , 56 ( 5 ), 705 - 733 .
Zhao Z. G. ; Zhuo S. Y. ; Fang R. C. ; Zhang L. H. ; Zhou X. T. ; Xu Y. C. ; Zhang J. Q. ; Dong Z. C. ; Jiang L. ; Liu M. J. Dual-programmable shape-morphing and self-healing organohydrogels through orthogonal supramolecular heteronetworks . Adv. Mater. , 2018 , 30 ( 51 ), 1804435 . doi: 10.1002/adma.201804435 http://dx.doi.org/10.1002/adma.201804435
Liu M. J. ; Wang S. T. ; Jiang L. Nature-inspired superwettability systems . Nat. Rev. Mater. , 2017 , 2 ( 7 ), 17036 . doi: 10.1038/natrevmats.2017.36 http://dx.doi.org/10.1038/natrevmats.2017.36
Zhu T. ; Jiang C. ; Wang M. L. ; Zhu C. Z. ; Zhao N. ; Xu J. Skin-inspired double-hydrophobic-coating encapsulated hydrogels with enhanced water retention capacity . Adv. Funct. Mater. , 2021 , 31 ( 27 ), 2102433 . doi: 10.1002/adfm.202102433 http://dx.doi.org/10.1002/adfm.202102433
Subraveti S. N. ; Raghavan S. R. A simple way to synthesize a protective "skin" around any hydrogel . ACS Appl. Mater. Interfaces , 2021 , 13 ( 31 ), 37645 - 37654 . doi: 10.1021/acsami.1c09460 http://dx.doi.org/10.1021/acsami.1c09460
Xiao W. Y. ; Wan X. Z. ; Shi L. X. ; Ye M. S. ; Zhang Y. K. ; Wang S. T. A viscous-biofluid self-pumping organohydrogel dressing to accelerate diabetic wound healing . Adv. Mater. , 2024 , 36 ( 25 ), 2401539 . doi: 10.1002/adma.202401539 http://dx.doi.org/10.1002/adma.202401539
Yao X. ; Chen L. ; Ju J. ; Li C. H. ; Tian Y. ; Jiang L. ; Liu M. J. Superhydrophobic diffusion barriers for hydrogels via confined interfacial modification . Adv. Mater. , 2016 , 28 ( 34 ), 7383 - 7389 . doi: 10.1002/adma.201601568 http://dx.doi.org/10.1002/adma.201601568
Du T. ; Ma S. H. ; Pei X. W. ; Wang S. T. ; Zhou F. Bio-inspired design and fabrication of micro/nano-brush dual structural surfaces for switchable oil adhesion and antifouling . Small , 2017 , 13 ( 4 ), 1602020 . doi: 10.1002/smll.201602020 http://dx.doi.org/10.1002/smll.201602020
Liao H. G. ; Hu S. ; Yang H. ; Wang L. ; Tanaka S. ; Takigawa I. ; Li W. ; Fan H. L. ; Gong J. P. Data-driven de novo design of super-adhesive hydrogels . Nature , 2025 , 644 ( 8075 ), 89 - 95 . doi: 10.1038/s41586-025-09269-4 http://dx.doi.org/10.1038/s41586-025-09269-4
Yuk H. ; Zhang T. ; Lin S. T. ; Parada G. A. ; Zhao X. H. Tough bonding of hydrogels to diverse non-porous surfaces . Nat. Mater. , 2016 , 15 ( 2 ), 190 - 196 . doi: 10.1038/nmat4463 http://dx.doi.org/10.1038/nmat4463
Li J. ; Celiz A. D. ; Yang J. ; Yang Q. ; Wamala I. ; Whyte W. ; Seo B. R. ; Vasilyev N. V. ; Vlassak J. J. ; Suo Z. ; Mooney D. J. Tough adhesives for diverse wet surfaces . Science , 2017 , 357 ( 6349 ), 378 - 381 . doi: 10.1126/science.aah6362 http://dx.doi.org/10.1126/science.aah6362
Yang S. ; Qin C. X. ; Zhang Z. Z. ; Zhang M. ; Li B. ; Ma Y. F. ; Zhou F. ; Liu W. M. Light-controlled adhesive hydrogels for on-demand adhesion . Chem Bio Eng. , 2025 , 2 ( 4 ), 253 - 259 . doi: 10.1021/cbe.4c00177 http://dx.doi.org/10.1021/cbe.4c00177
Rao P. ; Sun T. L. ; Chen L. ; Takahashi R. ; Shinohara G. ; Guo H. ; King D. R. ; Kurokawa T. ; Gong J. P. Tough hydrogels with fast, strong, and reversible underwater adhesion based on a multiscale design . Adv. Mater. , 2018 , 30 ( 32 ), 1801884 . doi: 10.1002/adma.201801884 http://dx.doi.org/10.1002/adma.201801884
Wang Z. Y. ; Chen D. Y. ; Wang H. Y. ; Bao S. Y. ; Lang L. P. ; Cui C. Y. ; Song H. T. ; Yang J. H. ; Liu W. G. The unprecedented biodegradable polyzwitterion: a removal-free patch for accelerating infected diabetic wound healing . Adv. Mater. , 2024 , 36 ( 30 ), 2404297 . doi: 10.1002/adma.202404297 http://dx.doi.org/10.1002/adma.202404297
Liu J. ; Tan C. S. Y. ; Scherman O. A. Dynamic interfacial adhesion through cucurbit[ n ] uril molecular recognition . Angew. Chim. Int. Ed. , 2018 , 57 ( 29 ), 8854 - 8858 . doi: 10.1002/anie.201800775 http://dx.doi.org/10.1002/anie.201800775
Li J. H. ; Chen M. J. ; Cheng S. W. ; Gao S. G. ; Zhai J. M. ; Yu D. M. ; Wang J. P. ; Zhang J. B. ; Cai K. Y. Sensorable zwitterionic antibacterial hydrogel for wound electrostimulation therapy . Biomaterials , 2025 , 315 , 122958 . doi: 10.1016/j.biomaterials.2024.122958 http://dx.doi.org/10.1016/j.biomaterials.2024.122958
Yang X. X. ; Luo Z. ; Shao J. X. ; Feng X. Q. ; Xu Z. Y. ; Cui C. Y. ; Liu W. G. Betaine-stabilized poly(lipoic acid) adhesive patch for oral ulcer treatment . Chinese J. Polym. Sci. , 2026 , 44 ( 5 ), 1444 - 1456 . doi: 10.1007/s10118-026-3592-y http://dx.doi.org/10.1007/s10118-026-3592-y
Yuk H. ; Varela C. E. ; Nabzdyk C. S. ; Mao X. Y. ; Padera R. F. ; Roche E. T. ; Zhao X. H. Dry double-sided tape for adhesion of wet tissues and devices . Nature , 2019 , 575 ( 7781 ), 169 - 174 . doi: 10.1038/s41586-019-1710-5 http://dx.doi.org/10.1038/s41586-019-1710-5
Won D. ; Kim H. ; Kim J. ; Kim H. ; Kim M. W. ; Ahn J. ; Min K. ; Lee Y. ; Hong S. ; Choi J. ; Kim C. Y. ; Kim T. S. ; Ko S. H. Laser-induced wet stability and adhesion of pure conducting polymer hydrogels . Nat. Electron. , 2024 , 7 ( 6 ), 475 - 486 . doi: 10.1038/s41928-024-01161-9 http://dx.doi.org/10.1038/s41928-024-01161-9
Zhang Y. ; Wu L. ; Zou M. M. ; Zhang L. D. ; Song Y. L. Suppressing the step effect of 3D printing for constructing contact lenses . Adv. Mater. , 2022 , 34 ( 4 ), 2107249 . doi: 10.1002/adma.202270030 http://dx.doi.org/10.1002/adma.202270030
Si M. Q. ; Feng W. H. ; Liu D. P. ; Hong W. ; Chen C. ; Hernandez A. ; Wong Y. H. C. ; Zuo X. B. ; Zhou H. ; Lu W. ; Chen T. ; He X. M. Programmable multicolor room-temperature phosphorescence hydrogels via the synergy of freeze-soaking and salting-out . Adv. Mater. , 2026 , 38 ( 9 ), e 18652 . doi: 10.1002/adma.202518652 http://dx.doi.org/10.1002/adma.202518652
AlQattan B. ; Yetisen A. K. ; Butt H. Direct laser writing of nanophotonic structures on contact lenses . ACS Nano , 2018 , 12 ( 6 ), 5130 - 5140 . doi: 10.1021/acsnano.8b00222 http://dx.doi.org/10.1021/acsnano.8b00222
Ding B. F. ; Zeng P. Y. ; Huang Z. Y. ; Dai L. X. ; Lan T. S. ; Xu H. ; Pan Y. K. ; Luo Y. T. ; Yu Q. M. ; Cheng H. M. ; Liu B. L. A 2D material-based transparent hydrogel with engineerable interference colours . Nat. Commun. , 2022 , 13 , 1212 . doi: 10.1038/s41467-021-26587-z http://dx.doi.org/10.1038/s41467-021-26587-z
Li J. Y. ; Mooney D. J. Designing hydrogels for controlled drug delivery . Nat. Rev. Mater. , 2016 , 1 , 16071 . doi: 10.1038/natrevmats.2016.71 http://dx.doi.org/10.1038/natrevmats.2016.71
Duan N. ; Luo X. R. ; Zhou Y. D. ; Chai J. Y. ; Wang J. Z. ; Gao J. ; Ye H. F. ; Shan S. Y. ; Liu Y. ; Yu C. C. Facile synthesis of an injectable redox/pH dual stimuli-responsive hydrogel system for drug release . Chinese J. Polym. Sci. , 2026 , 44 ( 4 ), 1114 - 1125 . doi: 10.1007/s10118-026-3558-0 http://dx.doi.org/10.1007/s10118-026-3558-0
Um E. ; Cho Y. K. ; Jeong J. Spontaneous wrinkle formation on hydrogel surfaces using photoinitiator diffusion from oil-water interface . ACS Appl. Mater. Interfaces , 2021 , 13 ( 13 ), 15837 - 15846 . doi: 10.1021/acsami.1c00449 http://dx.doi.org/10.1021/acsami.1c00449
Di J. ; Yao S. S. ; Ye Y. Q. ; Cui Z. ; Yu J. C. ; Ghosh T. K. ; Zhu Y. ; Gu Z. Stretch-triggered drug delivery from wearable elastomer films containing therapeutic depots . ACS Nano , 2015 , 9 ( 9 ), 9407 - 9415 . doi: 10.1021/acsnano.5b03975 http://dx.doi.org/10.1021/acsnano.5b03975
Bai T. ; Han Y. J. ; Zhang P. ; Wang W. ; Liu W. G. Zinc ion-triggered two-way macro-/ microscopic shape changing and memory effects in high strength hydrogels with pre-programmed unilateral patterned surfaces . Soft Matter , 2012 , 8 ( 25 ), 6846 - 6852 . doi: 10.1039/c2sm07364a http://dx.doi.org/10.1039/c2sm07364a
Chong J. ; Sung C. ; Nam K. S. ; Kang T. ; Kim H. ; Lee H. ; Park H. ; Park S. ; Kang J. Highly conductive tissue-like hydrogel interface through template-directed assembly . Nat. Commun. , 2023 , 14 , 2206 . doi: 10.1038/s41467-023-37948-1 http://dx.doi.org/10.1038/s41467-023-37948-1
Müller E. ; Pompe T. ; Freudenberg U. ; Werner C. Solvent-assisted micromolding of biohybrid hydrogels to maintain human hematopoietic stem and progenitor cells ex vivo . Adv. Mater. , 2017 , 29 ( 42 ), 1703489 . doi: 10.1002/adma.201703489 http://dx.doi.org/10.1002/adma.201703489
Meng H. ; Xiao P. ; Gu J. C. ; Wen X. F. ; Xu J. ; Zhao C. Z. ; Zhang J. W. ; Chen T. Self-healable macro-/microscopic shape memory hydrogels based on supramolecular interactions . Chem. Commun. , 2014 , 50 ( 82 ), 12277 - 12280 . doi: 10.1039/c4cc04760e http://dx.doi.org/10.1039/c4cc04760e
Matsuda T. ; Kawakami R. ; Namba R. ; Nakajima T. ; Gong J. P. Mechanoresponsive self-growing hydrogels inspired by muscle training . Science , 2019 , 363 ( 6426 ), 504 - 508 . doi: 10.1126/science.aau9533 http://dx.doi.org/10.1126/science.aau9533
Lee J. ; Silberstein M. N. ; Abdeen A. A. ; Kim S. Y. ; Kilian K. A. Mechanochemical functionalization of disulfide linked hydrogels . Mater. Horiz. , 2016 , 3 ( 5 ), 447 - 451 . doi: 10.1039/c6mh00091f http://dx.doi.org/10.1039/c6mh00091f
Deng J. W. ; Liu D. Y. ; Liu H. Q. ; Yu L. X. ; Bai Y. H. ; Xiao J. S. ; Wang H. L. Persistent room-temperature phosphorescent organohydrogels based on nonaromatic luminogens crosslinked by hydrogen bonds . Adv. Funct. Mater. , 2024 , 34 ( 48 ), 2408821 . doi: 10.1002/adfm.202408821 http://dx.doi.org/10.1002/adfm.202408821
Xu M. D. ; Hua L. Q. ; Gong L. H. ; Lu J. L. ; Wang J. H. ; Zhao C. Z. Lighted up by hydrogen-bonding: luminescence behavior and applications of AIEgen-doped interpenetrating network hydrogel . Sci. China Chem. , 2021 , 64 ( 10 ), 1770 - 1777 . doi: 10.1007/s11426-021-1056-4 http://dx.doi.org/10.1007/s11426-021-1056-4
Ding A. X. ; Tang F. ; Ayyagari S. ; Alsberg E. Reprogrammable 4D tissue engineering hydrogel scaffold via reversible ion printing . Bioact. Mater. , 2026 , 62 , 282 - 293 . doi: 10.1016/j.bioactmat.2026.03.011 http://dx.doi.org/10.1016/j.bioactmat.2026.03.011
Peng X. ; Li Y. ; Zhang Q. ; Shang C. ; Bai Q. W. ; Wang H. L. Tough hydrogels with programmable and complex shape deformations by ion dip-dyeing and transfer printing . Adv. Funct. Mater. , 2016 , 26 ( 25 ), 4491 - 4500 . doi: 10.1002/adfm.201601389 http://dx.doi.org/10.1002/adfm.201601389
Wen X. ; Zhang K. H. ; Wu B. Y. ; Chen G. C. ; Zheng N. ; Wu J. J. ; Yang X. X. ; Xie T. ; Zhao Q. Multi-mode geometrically gated encryption with 4D morphing hydrogel . Nat. Commun. , 2025 , 16 ( 1 ), 2830 . doi: 10.1038/s41467-025-58041-9 http://dx.doi.org/10.1038/s41467-025-58041-9
Lu Y. H. ; University Z. ; Zhang C. K. ; University Z. ; Xie T. ; University Z. ; Wu J. J. ; University Z. ; Center N. I. ; University Z. Grayscale color 3D/4D printing via orthogonal photochemistry . Chem Bio Eng. , 2024 , 1 ( 1 ), 76 - 82 . doi: 10.1021/cbe.3c00088 http://dx.doi.org/10.1021/cbe.3c00088
Yang C. ; Zheng W. Z. ; Ni C. J. ; Li Y. ; Chen D. ; Xie T. ; Zhao Q. Reconfigurable and orthogonal stiffness-structure patterning of dynamically crosslinked amphigels . SmartMat , 2024 , 5 ( 2 ), e 1255 . doi: 10.1002/smm2.1255 http://dx.doi.org/10.1002/smm2.1255
Xue L. L. ; Xiong X. H. ; Krishnan B. P. ; Puza F. ; Wang S. ; Zheng Y. J. ; Cui J. X. Light-regulated growth from dynamic swollen substrates for making rough surfaces . Nat. Commun. , 2020 , 11 , 963 . doi: 10.1038/s41467-020-14807-x http://dx.doi.org/10.1038/s41467-020-14807-x
Chen D. ; University Z. ; University Z. ; Wang H. J. ; University Z. ; Institute P. ; University Z. ; Ni C. J. ; University Z. ; Chen J. Y. ; University Z. ; Guo Y. J. ; University Z. ; Chen Z. ; University Z. ; Zheng N. ; University Z. ; Wu J. J. ; University Z. ; Ren H. ; University Z. ; Zhao Q. ; University Z. ; University Z. Light-regulated microstructure growth of dynamic hydrogels for flexible manufacturing of microlens arrays . Chem Bio Eng. , 2025 , 2 ( 6 ), 350 - 357 . doi: 10.1021/cbe.5c00007 http://dx.doi.org/10.1021/cbe.5c00007
Mora-Boza A. ; Mulero-Russe A. ; Di Caprio N. ; Burdick J. A. ; O'Neill E. ; Singh A. ; García A. J. Facile photopatterning of perfusable microchannels in hydrogels for microphysiological systems . Nat. Protoc. , 2025 , 20 ( 1 ), 272 - 292 . doi: 10.1038/s41596-024-01041-8 http://dx.doi.org/10.1038/s41596-024-01041-8
Kloxin A. M. ; Kasko A. M. ; Salinas C. N. ; Anseth K. S. Photodegradable hydrogels for dynamic tuning of physical and chemical properties . Science , 2009 , 324 ( 5923 ), 59 - 63 . doi: 10.1126/science.1169494 http://dx.doi.org/10.1126/science.1169494
Li L. ; Scheiger J. M. ; Tronser T. ; Long C. ; Demir K. ; Wilson C. L. ; Kuzina M. A. ; Levkin P. A. Inherent photodegradability of polymethacrylate hydrogels: straightforward access to biocompatible soft microstructures . Adv. Funct. Mater. , 2019 , 29 ( 33 ), 1902906 . doi: 10.1002/adfm.201902906 http://dx.doi.org/10.1002/adfm.201902906
Ni C. J. ; Chen D. ; Wen X. ; Jin B. J. ; He Y. ; Xie T. ; Zhao Q. High speed underwater hydrogel robots with programmable motions powered by light . Nat. Commun. , 2023 , 14 ( 1 ), 7672 . doi: 10.1038/s41467-023-43576-6 http://dx.doi.org/10.1038/s41467-023-43576-6
Fairbanks B. D. ; Singh S. P. ; Bowman C. N. ; Anseth K. S. Photodegradable, photoadaptable hydrogels via radical-mediated disulfide fragmentation reaction . Macromolecules , 2011 , 44 ( 8 ), 2444 - 2450 . doi: 10.1021/ma200202w http://dx.doi.org/10.1021/ma200202w
Chen D. ; Zhang Y. ; Ni C. J. ; Ma C. ; Yin J. ; Bai H. ; Luo Y. W. ; Huang F. H. ; Xie T. ; Zhao Q. Drilling by light: ice-templated photo-patterning enabled by a dynamically crosslinked hydrogel . Mater. Horiz. , 2019 , 6 ( 5 ), 1013 - 1019 . doi: 10.1039/c9mh00090a http://dx.doi.org/10.1039/c9mh00090a
Huang J. C. ; Qiu L. T. ; Ni C. J. ; Chen G. C. ; Zhao Q. Shape memory polymers with patternable recovery onset regulated by light . Adv. Mater. , 2024 , 36 ( 39 ), 2408324 . doi: 10.1002/adma.202408324 http://dx.doi.org/10.1002/adma.202408324
Wang H. ; Xiong X. H. ; Luo H. ; Cui Y. B. ; Wu Q. ; Fang Y. L. ; Chen J. ; Jing G. Y. ; Cui J. X. Transpiration-induced self-growth of texture hydrogel surfaces . Angew. Chim. Int. Ed. , 2024 , 63 ( 34 ), e 202407125 . doi: 10.1002/anie.202407125 http://dx.doi.org/10.1002/anie.202407125
Amir F. ; Liles K. P. ; Delawder A. O. ; Colley N. D. ; Palmquist M. S. ; Linder H. R. ; Sell S. A. ; Barnes J. C. Reversible hydrogel photopatterning: spatial and temporal control over gel mechanical properties using visible light photoredox catalysis . ACS Appl. Mater. Interfaces , 2019 , 11 ( 27 ), 24627 - 24638 . doi: 10.1021/acsami.9b08853 http://dx.doi.org/10.1021/acsami.9b08853
Zhu C. N. ; Bai T. W. ; Wang H. ; Ling J. ; Huang F. H. ; Hong W. ; Zheng Q. ; Wu Z. L. Dual-encryption in a shape-memory hydrogel with tunable fluorescence and reconfigurable architecture . Adv. Mater. , 2021 , 33 ( 29 ), 2102023 . doi: 10.1002/adma.202102023 http://dx.doi.org/10.1002/adma.202102023
Gao Y. ; Wang P. Y. ; Zhao F. ; Liu X. ; Wu J. P. ; Hu J. A facile approach for anisotropic hydrogel with light-regulated stiffness and its application to achieve mechanical toughening . Macromol. Rapid Commun. , 2022 , 43 ( 10 ), 2200077 . doi: 10.1002/marc.202200077 http://dx.doi.org/10.1002/marc.202200077
Zhao X. Y. ; Xu H. D. ; Liu Z. T. ; Li G. ; Jiang J. Q. ; Liu Z. W. Designable polypyrrole pattern in hydrogel achieved by photo-controllable concentration of Fe 3+ initiator . Smart Mol. , 2024 , 2 ( 3 ), e 20240015 . doi: 10.1002/smo.20240015 http://dx.doi.org/10.1002/smo.20240015
Chen D. ; Ni C. J. ; Xie L. L. ; Li Y. ; Deng S. H. ; Zhao Q. ; Xie T. Homeostatic growth of dynamic covalent polymer network toward ultrafast direct soft lithography . Sci. Adv. , 2021 , 7 ( 43 ), eabi 7360 . doi: 10.1126/sciadv.abi7360 http://dx.doi.org/10.1126/sciadv.abi7360
Yin M. J. ; Yao M. ; Gao S. R. ; Zhang A. P. ; Tam H. Y. ; Wai P. A. Rapid 3D patterning of Poly(acrylic acid) ionic hydrogel for miniature pH sensors . Adv. Mater. , 2016 , 28 ( 7 ), 1394 - 1399 . doi: 10.1002/adma.201504021 http://dx.doi.org/10.1002/adma.201504021
Wu J. J. ; Huang L. M. ; Zhao Q. ; Xie T. 4D printing: history and recent progress . Chinese J. Polym. Sci. , 2018 , 36 ( 5 ), 563 - 575 . doi: 10.1007/s10118-018-2089-8 http://dx.doi.org/10.1007/s10118-018-2089-8
Huang L. M. ; Jiang R. Q. ; Wu J. J. ; Song J. Z. ; Bai H. ; Li B. G. ; Zhao Q. ; Xie T. Ultrafast digital printing toward 4D shape changing materials . Adv. Mater. , 2017 , 29 ( 7 ), 1605390 . doi: 10.1002/adma.201605390 http://dx.doi.org/10.1002/adma.201605390
Kang J. Y. ; Zhang X. W. ; Yang X. Y. ; Yang X. H. ; Wang S. T. ; Song W. L. Mucosa-inspired electro-responsive lubricating supramolecular-covalent hydrogel . Adv. Mater. , 2023 , 35 ( 46 ), 2307705 . doi: 10.1002/adma.202307705 http://dx.doi.org/10.1002/adma.202307705
Morales D. ; Podolsky I. ; Mailen R. W. ; Shay T. ; Dickey M. D. ; Velev O. D. Ionoprinted multi-responsive hydrogel actuators . Micromachines , 2016 , 7 ( 6 ), 98 . doi: 10.3390/mi7060098 http://dx.doi.org/10.3390/mi7060098
Zhang Y. L. ; Wang Y. ; Wang H. ; Yu Y. ; Zhong Q. F. ; Zhao Y. J. Super-elastic magnetic structural color hydrogels . Small , 2019 , 15 ( 35 ), 1902198 . doi: 10.1002/smll.201902198 http://dx.doi.org/10.1002/smll.201902198
Li Z. ; Yao M. T. ; Qiu Z. Y. ; Xu J. K. ; Lu B. Y. Fe 3+ -coordinated dual-crosslinked conjugated polymer hydrogels with ultrahigh evaporation rate for efficient desalination and sustainable agriculture . Chinese J. Polym. Sci. , 2026 , 44 ( 3 ), 632 - 643 . doi: 10.1007/s10118-025-3543-z http://dx.doi.org/10.1007/s10118-025-3543-z
He C. F. ; Chen X. C. ; Sun Y. ; Xie M. J. ; Yu K. ; He J. ; Lu J. W. ; Gao Q. ; Nie J. ; Wang Y. ; He Y. Rapid and mass manufacturing of soft hydrogel microstructures for cell patterns assisted by 3D printing . Bio Des. Manuf. , 2022 , 5 ( 4 ), 641 - 659 . doi: 10.1007/s42242-022-00207-1 http://dx.doi.org/10.1007/s42242-022-00207-1
Zhao S. W. ; Chen Y. ; Partlow B. P. ; Golding A. S. ; Tseng P. ; Coburn J. ; Applegate M. B. ; Moreau J. E. ; Omenetto F. G. ; Kaplan D. L. Bio-functionalized silk hydrogel microfluidic systems . Biomaterials , 2016 , 93 , 60 - 70 . doi: 10.1016/j.biomaterials.2016.03.041 http://dx.doi.org/10.1016/j.biomaterials.2016.03.041
Yu W. H. ; Liu X. J. ; Liu Y. W. ; Chen X. ; Ge S. H. ; Dong Z. Q. 3 D printing of phase-separating hydrogels with tunable microachitecture for mechanoregulated bone regeneration . Adv. Funct. Mater. , 2026 , 36 ( 30 ), e 23349 . doi: 10.1002/adfm.202523349 http://dx.doi.org/10.1002/adfm.202523349
You D. Q. ; Chen G. C. ; Liu C. ; Ye X. ; Wang S. L. ; Dong M. Y. ; Sun M. Y. ; He J. X. ; Yu X. W. ; Ye G. C. ; Li Q. ; Wu J. J. ; Wu J. J. ; Zhao Q. ; Xie T. ; Yu M. F. ; Wang H. M. 4D printing of multi-responsive membrane for accelerated in vivo bone healing via remote regulation of stem cell fate . Adv. Funct. Mater. , 2021 , 31 ( 40 ), 2103920 . doi: 10.1002/adfm.202103920 http://dx.doi.org/10.1002/adfm.202103920
Lan X. Y. ; Xu S. S. ; Sun C. X. ; Zheng Y. ; Wang B. ; Shan G. R. ; Bao Y. Z. ; Yu C. T. ; Pan P. J. Multi-level information encryption/decryption of fluorescent hydrogels based on spatially programmed crystal phases . Small , 2023 , 19 ( 9 ), 2205960 . doi: 10.1002/smll.202205960 http://dx.doi.org/10.1002/smll.202205960
Deng J. W. ; Wu H. R. ; Xie W. D. ; Jia H. Y. ; Xia Z. G. ; Wang H. L. Metal cation-responsive and excitation-dependent nontraditional multicolor fluorescent hydrogels for multidimensional information encryption . ACS Appl. Mater. Interfaces , 2021 , 13 ( 33 ), 39967 - 39975 . doi: 10.1021/acsami.1c12604 http://dx.doi.org/10.1021/acsami.1c12604
Le X. X. ; Lu W. ; He J. ; Serpe M. J. ; Zhang J. W. ; Chen T. Ionoprinting controlled information storage of fluorescent hydrogel for hierarchical and multi-dimensional decryption . Sci. China Mater. , 2019 , 62 ( 6 ), 831 - 839 . doi: 10.1007/s40843-018-9372-2 http://dx.doi.org/10.1007/s40843-018-9372-2
Chen Z. ; Chen Y. J. ; Guo Y. T. ; Yang Z. ; Li H. ; Liu H. Z. Paper-structure inspired multiresponsive hydrogels with solvent-induced reversible information recording, self-encryption, and multidecryption . Adv. Funct. Mater. , 2022 , 32 ( 23 ), 2201009 . doi: 10.1002/adfm.202201009 http://dx.doi.org/10.1002/adfm.202201009
Chen D. ; Ni C. J. ; Yang C. ; Li Y. ; Wen X. ; Frank C. W. ; Xie T. ; Ren H. ; Zhao Q. Orthogonal photochemistry toward direct encryption of a 3D-printed hydrogel . Adv. Mater. , 2023 , 35 ( 14 ), 2209956 . doi: 10.1002/adma.202209956 http://dx.doi.org/10.1002/adma.202209956
Yu C. ; Jiang Z. Y. ; Han J. Y. ; Yue C. J. ; Wei M. ; Wang W. Q. ; Chen T. ; Lu W. Fe 3+ /Zr 4+ dual-responsive distinct yet reversible fluorescence of polymeric hydrogels for rewritable information encryption with time-dependent security . Adv. Funct. Mater. , 2026 , 36 ( 1 ), e 11045 . doi: 10.1002/adfm.202511045 http://dx.doi.org/10.1002/adfm.202511045
Ge G. ; Lu Y. ; Qu X. Y. ; Zhao W. ; Ren Y. F. ; Wang W. J. ; Wang Q. ; Huang W. ; Dong X. C. Muscle-inspired self-healing hydrogels for strain and temperature sensor . ACS Nano , 2020 , 14 ( 1 ), 218 - 228 . doi: 10.1021/acsnano.9b07874 http://dx.doi.org/10.1021/acsnano.9b07874
Qiao H. Y. ; Sun S. T. ; Wu P. Y. Non-equilibrium-growing aesthetic ionic skin for fingertip-like strain-undisturbed tactile sensation and texture recognition . Adv. Mater. , 2023 , 35 ( 21 ), 2300593 . doi: 10.1002/adma.202300593 http://dx.doi.org/10.1002/adma.202300593
耿悦 . 高分子功能材料图案化制备及其在光电领域的应用 . 高分子学报 , 2020 , 51 ( 5 ):
■-■ .
Ji B. ; Yue J. Y. ; Zhou Q. ; Fang Y. ; Zheng B. ; Wang J. F. ; Zhai Y. X. ; Zhou B. P. ; Tang D. S. Localized gradient conductivity enabled ultrasensitive flexible tactile sensors with ultrawide linearity range . Adv. Mater. , 2026 , 38 ( 1 ), e 11275 . doi: 10.1002/adma.202511275 http://dx.doi.org/10.1002/adma.202511275
Qin D. E. ; Liu C. Y. ; Song K. L. ; Ramakrishna S. Bioinspired silk fibroin/poly-acrylic acid high-performance hydrogel sensors with micro-architecture prepared by rapid polymerization via TA-Fe 3 O 4 @MXene catalytic system . Chem. Eng. J. , 2025 , 525 , 170300 . doi: 10.1016/j.cej.2025.170300 http://dx.doi.org/10.1016/j.cej.2025.170300
Ren H. W. ; Li W. Y. ; Li H. X. ; Ding Y. N. ; Li J. Y. ; Feng Y. M. ; Su Z. ; Zhang X. ; Jiang L. ; Liu H. ; Hu P. G. Jellyfish-inspired high-sensitivity pressure-temperature sensor . Adv. Funct. Mater. , 2025 , 35 ( 12 ), 2417715 . doi: 10.1002/adfm.202417715 http://dx.doi.org/10.1002/adfm.202417715
Tao K. ; Chen Z. S. ; Yu J. H. ; Zeng H. Z. ; Wu J. ; Wu Z. X. ; Jia Q. Y. ; Li P. ; Fu Y. Q. ; Chang H. L. ; Yuan W. Z. Ultra-sensitive, deformable, and transparent triboelectric tactile sensor based on micro-pyramid patterned ionic hydrogel for interactive human-machine interfaces . Adv. Sci. , 2022 , 9 ( 10 ), 2104168 . doi: 10.1002/advs.202104168 http://dx.doi.org/10.1002/advs.202104168
Tian X. Y. ; Sun M. W. ; Wen G. Y. ; Cao M. ; Pan D. W. ; Xie R. ; Ju X. J. ; Liu Z. ; Wang W. ; Chu L. Y. Ultrasensitive hydrogel grating detector for real-time continuous-flow detection of trace threat Pb 2+ . J. Hazard. Mater. , 2023 , 443 , 130289 . doi: 10.1016/j.jhazmat.2022.130289 http://dx.doi.org/10.1016/j.jhazmat.2022.130289
Sun Z. Y. ; Ou Q. D. ; Dong C. ; Zhou J. S. ; Hu H. Y. ; Li C. ; Huang Z. D. Conducting polymer hydrogels based on supramolecular strategies for wearable sensors . Exploration , 2024 , 4 ( 5 ), 20220167 . doi: 10.1002/exp.20220167 http://dx.doi.org/10.1002/exp.20220167
Zhou Y. J. ; Zhang L. Y. ; Liu S. F. ; Wei Y. ; Hu Y. C. ; Lian X. J. ; Wang L. F. ; Liang Z. W. ; Chen W. Y. ; Xie X. ; Huang D. Bonding of hydrogel to biometal surfaces: principles, methods and applications . Exploration , 2025 , 5 ( 5 ), 20240049 . doi: 10.1002/exp.20240049 http://dx.doi.org/10.1002/exp.20240049
0
Views
0
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution

京公网安备11010802046899号