PLA/MWNT/HA hybrid nanofibers were prepared via electrospinning technology．Multi-wailed carbon nanotabe (MWNT) wem first treated by anodie oxidation

which resu／ted in various functional groups such as C一O

C一O and O—C=O on the surface of oxidized MWNT．Then the MWNT/hydroxyapatite (HA) nano-composites (MWNT content 3 wt％) were in situ synthesized by wet method with the help of ultrasonic treatment．Because of the strong interaction between the functional groups on the surface of MWNT and C2+ in HA．the obtained HA nano-particles were deposited onto the surface of oxidized MWNT．The as-received MWNT/HA nano-composites with excellent biocompatibility and osteoinduction were introduced into a bioabsorbable polymer

polylactide (PLA)

and the PLA/MWNT/HA hybrid nanofibers were electrospun through a double solvent method under the voltage of 18 kV and the capillary to target distance was 4 cm．The structure and morphology of hybrid nanofibers were characterized by SEM．Because of the nanoscaled diameters

miemscaled interconnected pores and suitable surface chemistry

the hybrid nanofibers would match the requirements of ideal bone tissue engineering scaffold and may be a potential material for preparing bone tissue engineering scaffold.