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Published:20 August 2000,
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PENG Xianghong, ZHANG Lina. STUDIES ON THE STRUCTURE AND CONTROLLED RELEASE OF CHITOSAN/FIBROIN MICROSPHERE INCLUSION DRUG. [J]. Acta Polymerica Sinica (4):502-505(2000)
DOI:
PENG Xianghong, ZHANG Lina. STUDIES ON THE STRUCTURE AND CONTROLLED RELEASE OF CHITOSAN/FIBROIN MICROSPHERE INCLUSION DRUG. [J]. Acta Polymerica Sinica (4):502-505(2000) DOI:
Miscibility of the fibroin
which was soluble in CaCl2-H2O-C2H5OH aqueous solution
mixed with chitosan was investigated
and its microspheres were prepared. The chitosan (CS)/fibroin (FB) microsphere inclusion fenoprofen calcium (CS-FB-FC) was prepared
and its structure was analyzed by FTIR
X-ray and SEM. The results indicated that blend of chitosan
fibroin and fenoprofen calcium in aqueous solution is miscible
and strong interaction caused by intermolecular hydrogen bonding exits in CS-FB-FC. It was indicated that approximately the initial 6h
and with increasing the glutaraldehyde concentration
the release of fenoprofen decreased.
壳聚糖丝心蛋白非诺洛芬钙共混微球缓释
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