N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES

JIN Man-rong; ZHANG Gui-ying; WU Chang-fa; LIU Pei-yi; HOU Wei

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N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES

Research Article | 更新时间：2021-03-19

- N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES
- Acta Polymerica Sinica Issue 3, Pages: 321-326(1995)
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- Published：20 June 1995，
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JIN Man-rong, ZHANG Gui-ying, WU Chang-fa, LIU Pei-yi, HOU Wei. N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES. [J]. Acta Polymerica Sinica (3):321-326(1995)
DOI：

JIN Man-rong, ZHANG Gui-ying, WU Chang-fa, LIU Pei-yi, HOU Wei. N-ALKYL ACRYLAMIDE GELS AND THEIR TEMPERATURESENSITIVE PROPERTIES. [J]. Acta Polymerica Sinica (3):321-326(1995) DOI：

摘要

研制成功５种聚Ｎ－烷基丙烯酰胺类温敏凝胶：聚Ｎ－异丙基丙烯酰胺（ＰＮＩＰＡ），聚Ｎ－异丙基丙烯酰胺＋甲基丙烯酰胺（ＰＮＩＰＡ／ＭＡＡ），聚Ｎ，Ｎ－二乙基丙烯酰胺（ＰＮＤＥＡ），聚Ｎ－正丙基丙烯酰胺（ＰＮＮＰＡ），聚Ｎ，Ｎ－二乙基丙烯酰胺＋Ｎ－叔丁基丙烯酰胺（ＰＮＤＥＡ／ＮＴＢＡ），并系统研究了这些凝胶的温敏相交特性．以聚Ｎ－异丙基丙烯酰胺（ＰＮＩＰＡ）凝胶相交特性为基础的凝胶萃取过程对牛血清白蛋白和兰葡聚糖溶液的浓缩实验表明，凝胶萃取对于浓缩和制备贵重生化制品是很有效的．

Abstract

Poly-N-Alkyl acrylamide temperature-sensitive hydrogels (poly-N-isopropylamide

poly-N-isopropylacrylamide/methylacrylamide copolymer

poly-N

N-die-thylacrylamide

poly-N

N-diethylacrylamide/N-tert-butylactyamide copolymer and poly-N-n-propylamide) have been prepared.The temperature sensibilities

phase -transition as well as swelling-collapsing properties of the gels are discussed. Based on the performances of poly-N-isopropylacrylamide

the gel-extraction separation is examined to be an effective process for concentration of protein solutions.

关键词

聚N－烷基丙烯酰胺凝胶温敏性凝胶萃取分离相变温度

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