SYNTHESIS OF MACROPOROUS POLY-a-VINYLPYRIDINE RESINS AND ITS REMOVAL OF UNCONJUGATED BILIRUBIN

WANG Hui-ming; Chen Chang-zhi; TONG Ming-rong; ZHENG Jiu-tian; YU Yao-ting

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SYNTHESIS OF MACROPOROUS POLY-a-VINYLPYRIDINE RESINS AND ITS REMOVAL OF UNCONJUGATED BILIRUBIN

Research Article | 更新时间：2021-03-19

- SYNTHESIS OF MACROPOROUS POLY-a-VINYLPYRIDINE RESINS AND ITS REMOVAL OF UNCONJUGATED BILIRUBIN
- Acta Polymerica Sinica Issue 2, Pages: 171-176(1989)
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- Published：20 April 1989，
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WANG Hui-ming, Chen Chang-zhi, TONG Ming-rong, ZHENG Jiu-tian, YU Yao-ting. SYNTHESIS OF MACROPOROUS POLY-a-VINYLPYRIDINE RESINS AND ITS REMOVAL OF UNCONJUGATED BILIRUBIN. [J]. Acta Polymerica Sinica (2):171-176(1989)
DOI：

WANG Hui-ming, Chen Chang-zhi, TONG Ming-rong, ZHENG Jiu-tian, YU Yao-ting. SYNTHESIS OF MACROPOROUS POLY-a-VINYLPYRIDINE RESINS AND ITS REMOVAL OF UNCONJUGATED BILIRUBIN. [J]. Acta Polymerica Sinica (2):171-176(1989) DOI：

摘要

本文合成了交联聚α-乙烯基吡啶珠状树脂

对树脂的交联度及致孔剂等因素进行了探索。实验结果表明:交联度在10％、致孔剂用量为200％时

可获得高比表面积的树脂。聚α-乙烯基吡啶珠状树脂对胆红素的清除率可达91％。但共血液相容性较差

对血液中白细胞及血小板的破坏达50％。使用时需包膜。

Abstract

Macroporous poly-vinylpyridine resins with quaternary ammonium group were synthesized and the relationship between the ratio of crosslinking and diluent used was studied. Experimental results showed that resins with high specific surface area could be obtained with 10% crosslinking agent and 200% diuent. Removal of bilirubin by the above resin was 91%. The blood compatible properties were not satisfactory and 50% leukocytes and erythocytes remained after 2 hrs. of circulation.

关键词

聚α-乙烯基吡啶血液相容性未结合胆红素

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