Controlled Self-assembly of Large-sized Gold Nanoparticles by Block Copolymers

Tian-en Shui; Zhe Wang; Hai-ying Huang

doi:10.11777/j.issn1000-3304.2025.25065

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Controlled Self-assembly of Large-sized Gold Nanoparticles by Block Copolymers

Research Article | 更新时间：2026-05-11

- Controlled Self-assembly of Large-sized Gold Nanoparticles by Block Copolymers
  增强出版
- Acta Polymerica Sinica Vol. 56, Issue 11, Pages: 2067-2078(2025)
- 作者机构：
  
  1.长春工业大学材料科学与工程学院化学与生命科学学院长春 130012
  2.吉林省先进高分子功能膜材料重点实验室长春 130012
  3.中国科学院长春应用化学研究所高分子物理与化学国家重点实验室长春 130022
- 作者简介：
  
  Zhe Wang, E-mail: wangzhe@ccut.edu.cn
- 基金信息：
- DOI：10.11777/j.issn1000-3304.2025.25065
  CLC：
- CSTR：32057.14.GFZXB.2025.7431
- Received：24 April 2025，
  
  Accepted：12 July 2025，
  
  Online First：29 September 2025，
  
  Published：20 November 2025
- 稿件说明：
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水天恩, 王哲, 黄海瑛. 大尺寸金纳米粒子与嵌段共聚物的可控组装. 高分子学报, 2025, 56(11), 2067-2078

Shui, T. E.; Wang, Z.; Huang, H. Y. Controlled self-assembly of large-sized gold nanoparticles by block copolymers. Acta Polymerica Sinica, 2025, 56(11), 2067-2078
水天恩, 王哲, 黄海瑛. 大尺寸金纳米粒子与嵌段共聚物的可控组装. 高分子学报, 2025, 56(11), 2067-2078 DOI： 10.11777/j.issn1000-3304.2025.25065. CSTR： 32057.14.GFZXB.2025.7431.

Shui, T. E.; Wang, Z.; Huang, H. Y. Controlled self-assembly of large-sized gold nanoparticles by block copolymers. Acta Polymerica Sinica, 2025, 56(11), 2067-2078 DOI： 10.11777/j.issn1000-3304.2025.25065. CSTR： 32057.14.GFZXB.2025.7431.

摘要

嵌段共聚物(BCP)自组装行为在调控纳米粒子(NPs)的形貌与功能化应用中备受关注. 现有研究多集中于特征尺寸小于50 nm的纳米粒子体系，而很少针对大尺寸纳米粒子(

100 nm)的组装行为进行研究. 本研究通过胶束溶液热退火的方法，详细追踪了采用种子生长法合成的大尺寸金纳米粒子(

200 nm)与聚苯乙烯-聚四乙烯基吡啶-聚环氧乙烷(PS-

-P4VP-

-PEO)三嵌段共聚物胶束的共组装过程，并成功制备了单分散具有胶束状核壳结构的Au@PS-P4VP-PEO复合微球. 透射电子显微镜(TEM)、扫描透射电子显微镜(STEM)、原子力显微镜(AFM)和动态光散射(DLS)系统表征了复合微球的组成和结构. 研究认为在升温退火条件下，初始的嵌段共聚物胶束核心PS链段活动能力增强，胶束在界面相互作用和构象熵驱动下与大尺寸金纳米粒子共组装形成稳定的核壳结构. 同时，该策略也成功应用于PS-

-PEO二嵌段共聚物胶束体系，进一步证实它是一种简单、有效的制备大尺寸金属纳米粒子/聚合物复合材料的方法.

Abstract

The self-assembly behavior of block copolymers (BCPs) has attracted considerable attention in regulating the morphology and functionalization of nanoparticles (NPs) for diverse applications. While extensive research has focused on NP systems with feature sizes below 50 nm

studies on the assembly behavior of larger nanoparticles (

100 nm) remain limited. In this work

we report a detailed investigation of the co-assembly process between poly(styrene-

-4-vinyl pyridine-

-ethylene oxide) (PS-

-P4VP-

-PEO) triblock copolymer micelles and large-sized gold nanoparticles (

200 nm) synthesized via the seed growth method. By employing thermal annealing of micellar solutions

we successfully fabricated monodisperse Au@PS-P4VP-PEO composite microspheres with a core-shell nanostructure encapsulated by triblock copolymer micelles. The resulting structures were characterized using transmission electron microscopy (TEM)

scanning transmission electron microscopy (STEM)

atomic force microscopy (AFM)

and dynamic light scattering (DLS). Our findings suggest that the PS chains at the core of the initial micelles enhance their mobility under thermal annealing

facilitating co-assembly with large gold nanoparticles. Stable core-shell structures are formed through co-assembly

driven by interfacial interactions and conformational entropy. Furthermore

this strategy was successfully applied to poly(styrene-

-ethylene oxid

e) (PS-

-PEO) diblock copolymer micelles

demonstrating its versatility as a simple

effective

and efficient method for the fabrication of large sized metal nanoparticle-polymer composites.

关键词

Keywords

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