CHEN Fuping, HU Qiaoling, CHEN Liang, LI Baoqiang, SHEN Jiacong. EPARATION OF MAGNETIC IRON OXIDE/HYDROXYAPATITE/CHITOSAN RODS BY in situ PRECIPITATION[J]. Acta Polymerica Sinica, 2006,(6):756-760.
CHEN Fuping, HU Qiaoling, CHEN Liang, LI Baoqiang, SHEN Jiacong. EPARATION OF MAGNETIC IRON OXIDE/HYDROXYAPATITE/CHITOSAN RODS BY in situ PRECIPITATION[J]. Acta Polymerica Sinica, 2006,(6):756-760.DOI:
Chitosan(CS)is suggested for using in orthopedic applications to provide temporary mechanical support for the regeneration of bone cell ingrowth due to its good biocompatible
non-toxic
biodegradable
and inherent wound healing characteristics.In the present study magnetic iron oxide/hydroxyapafite(HA)/chitosan rods were prepared by blending magnetic iron oxide/hydroxyapatite with chitosan via in situ precipitation.Magnetic iron oxide/hydroxyapafite was obtained by co—precipitation method.X—ray diffraction(XRD)
size distribution and magnetic measurements were performed to characterize the as—prepared magnetic iron oxide/hydroxyapatite
the results confirmed the formation of magnetic iron oxide/hydroxyapatite with particle size of around 1380 nm
and its saturated magnetic intensity(Ms)was about 33.3 emu When the total inorganic and CS content kept constant
effect of the rafto of magnetic iron oxide and hydroxyapatite on the mechanical properties was invested
the reults showed that the best ratio of magnetic iron oxide and hydroxyapatite was 3:17
and the effect of the ratio of magnetic iron oxide/HA and chitosan on the mechanical properties was also investigated
9:91 was the best ratio.It could be also concluded from the three point bending test that the mechanical properties improved as the inorganic content decreased.Bending strength and bending modulus of the magnetic iron oxide/HA/CS composite were 87.0 MPa and 1.57 GPa
respectively.The mechanical pmperties of magnetic iron oxide/HA/CS composites were stronge while compared to those of human bones
due to the special performances of magnetic iron oxide and hydroxyapatite
this composite could have potential use in bone repair domain.The microstructure studies of magnetic iron oxide/hydroxyapatite/chitosan rods were carried out by scanning electron microscopy(SEM)
and SEM mierographs supported the results of the three point bending test.