柔性纤维生物电子复合材料与器件

郭悦; 王佳佳; 王立媛; 孙雪梅; 彭慧胜

doi:10.11777/j.issn1000-3304.2022.22051

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柔性纤维生物电子复合材料与器件

专论 | 更新时间：2024-10-08

- 柔性纤维生物电子复合材料与器件
- Flexible Fiber Bioelectronic Composite Materials and Devices
- 高分子学报 2022年53卷第7期页码：707-721
- 作者机构：
  
  聚合物分子工程国家重点实验室复旦大学高分子科学系先进材料实验室上海 200438
- 作者简介：
  
  [ "孙雪梅，女，1986年生. 复旦大学高分子科学系副教授，博士生导师. 2008年毕业于华东理工大学高分子材料与工程专业，获工学学士学位；2013年在复旦大学获得高分子化学与物理专业博士学位；毕业后在复旦大学从事博士后研究. 2015年加入复旦大学高分子科学系和聚合物分子工程国家重点实验室. 2021年获得国家自然科学基金优秀青年基金资助. 主要研究方向是功能高分子复合材料及其在柔性纤维生物电子器件领域的应用." ]
- 基金信息：
  
  国家自然科学基金(基金号52122310;22075050)
- DOI：10.11777/j.issn1000-3304.2022.22051
  中图分类号：
- 纸质出版日期：2022-07-20，
  
  网络出版日期：2022-06-01，
  
  收稿日期：2022-02-24，
  
  录用日期：2022-04-11
- 稿件说明：
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郭悦,王佳佳,王立媛等.柔性纤维生物电子复合材料与器件[J].高分子学报,2022,53(07):707-721.

Guo Yue,Wang Jia-jia,Wang Li-yuan,et al.Flexible Fiber Bioelectronic Composite Materials and Devices[J].ACTA POLYMERICA SINICA,2022,53(07):707-721.
郭悦,王佳佳,王立媛等.柔性纤维生物电子复合材料与器件[J].高分子学报,2022,53(07):707-721. DOI： 10.11777/j.issn1000-3304.2022.22051.

Guo Yue,Wang Jia-jia,Wang Li-yuan,et al.Flexible Fiber Bioelectronic Composite Materials and Devices[J].ACTA POLYMERICA SINICA,2022,53(07):707-721. DOI： 10.11777/j.issn1000-3304.2022.22051.

摘要

可穿戴和可植入的纤维生物电子器件可以实现对人体生理体征的实时监测和精准调控，在健康监测和疾病诊疗等领域发挥了革新作用. 然而，传统的纤维生物电子器件柔性不足而与生物软组织的力学性能不匹配，难以形成稳定的器件/组织界面，最终无法实现长期稳定工作. 本文重点介绍了近年来课题组针对上述问题在柔性纤维生物电子复合材料与器件方面的研究进展. 首先制备了具有杂化结构和芯鞘结构的柔性高分子复合纤维电极，并面向柔性生物电子器件要求，对纤维材料的电学和力学性能及生物安全性进行表征. 进一步，基于所制备的复合纤维电极，发展出一系列可穿戴和可植入的纤维生物电子器件，具有传感、能源、调控等功能，并通过建立稳定的器件/组织界面，实现了在体长期工作，在生物医学研究和智慧医疗等领域展现出良好的应用前景. 最后，展望了柔性纤维生物电子领域的未来发展方向.

Abstract

Wearable and implantable fiber bioelectronics can continuously collect physiological information and accurately modulate physiological environment

which have revolutionized the conventional way of health monitoring

disease diagnosis and treatment. However

most of the fiber bioelectronics reported so far have insufficient flexibility. They do not match the soft tissues mechanically and cannot form stable device/tissue interface

limiting their long-term use. In this feature article

we mainly introduced our recent progress on flexible fiber bioelectronic composite materials and devices

aiming to solve the problem above. We first introduced the fabrication of flexible polymer composite fibers with hybrid or core-sheath structure

which possess good electrical and mechanical properties as well as biocompatibility. Based on the high-performance flexible polymer composite fibers

a series of fiber bioelectronics with functions of biosensing

energy-harvesting and storage

and electrochemical modulating were constructed for wearable and implantable applications

which showed promising prospects in healthcare and medicine. Finally

we discussed the future development direction of flexible fiber bioelectronics.

关键词

高分子复合纤维碳纳米管柔性纤维生物电子器件

Keywords

Polymer composite fiberCarbon nanotubeFlexibleFiber bioelectronics

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