Studies on Amphiphilic Triblock Copolymer PHB-PEG-PHB and Its Nanoparticles

Xue-mei Li; Ji-dong He

doi:10.11777/j.issn1000-3304.2015.14166

您当前的位置：

首页 >

文章列表页 >

Studies on Amphiphilic Triblock Copolymer PHB-PEG-PHB and Its Nanoparticles

Research Article | 更新时间：2021-03-19

- Studies on Amphiphilic Triblock Copolymer PHB-PEG-PHB and Its Nanoparticles
- Acta Polymerica Sinica Issue 1, Pages: 41-48(2015)
- 作者机构：
  
  青岛科技大学橡塑材料与工程教育部重点实验室山东省橡塑材料与工程重点实验室,青岛,266042
- 作者简介：
- 基金信息：
- DOI：10.11777/j.issn1000-3304.2015.14166
  CLC：
- Published：20 January 2015，
扫描看全文
Xue-mei Li, Ji-dong He. Studies on Amphiphilic Triblock Copolymer PHB-PEG-PHB and Its Nanoparticles. [J]. Acta Polymerica Sinica (1):41-48(2015)
DOI：

Xue-mei Li, Ji-dong He. Studies on Amphiphilic Triblock Copolymer PHB-PEG-PHB and Its Nanoparticles. [J]. Acta Polymerica Sinica (1):41-48(2015) DOI： 10.11777/j.issn1000-3304.2015.14166.

摘要

基于聚(-丁内酯)(PHB)和聚乙二醇(PEG)的两亲性三嵌段共聚物聚(-丁内酯)-聚乙二醇-聚(-丁内酯)(PHB-PEG-PHB)可在聚乙二醇钾盐大分子引发剂的作用下、以四氢呋喃为溶剂

通过-丁内酯(BL)的阴离子开环聚合进行制备

调节BL与聚乙二醇钾盐的配比

可制备分子量不同的共聚物.产物可通过1H-NMR、13C-NMR、FTIR、DSC、GPC等测试进行表征

DSC结果表明无定形的PHB阻碍了PEG的结晶

且随着PHB链段长度的增加

阻碍作用更加明显.PHB-PEG-PHB可在水中通过沉淀/溶剂蒸发技术进行自组装形成具有核壳结构的纳米粒子

并通过SEM、DLS手段对其表征

发现粒子尺寸在纳米级

形态为球形或方形.聚合物的初始浓度对纳米粒子的形态和尺寸有明显影响

随着聚合物初始浓度的降低

纳米粒子的尺寸降低.

Abstract

New amphiphilic triblock copolymer poly(-butyrolactone)-poly(ethylene glycol)-poly(-butyrolactone) (PHB-PEG-PHB) based on poly(-butyrolactone) (PHB) and poly(ethylene glycol) (PEG) was synthesized by anionic ring-opening polymerization of BL initiated with PEG-potassium macroinitiators using tetrahydrofuran as solvent.Many Copolymers with different molecular weight were prepared by adjusting the ratio of monomer (BL) and macroinitiators.Copolymers were characterized by 1H-NMR

13C-NMR

FTIR

DSC

GPC.The DSC curves showed that amorphous PHB hindered the crystallization of the PEG block.The longer the PHB block length

the more obvious the hindering effect.These PHB-PEG-PHB copolymers were self-assembled into nanoparticles with core-shell structure by a precipitation/solvent evaporation technique in aqueous solutions.These nanoparticles were characterized by SEM and DLS.The nanoparticles size was nanoscale.Their shapes were spherical or square.The size and morphology of nanoparticles were related to the initial concentrations of copolymers.The results showed that the size of nanoparticles reduced with reducing the initial concentrations of copolymers.

关键词

两亲性三嵌段共聚物PHB-PEG-PHB聚乙二醇钾盐萘钾-冠醚引发体系开环共聚合纳米粒子

Keywords

AmphiphilicTriblock polymer PHB-PEG-PHBPoly(ethylene glycol)-potassiumNaphthalene potassium-crown ether initiator systemRing-opening copolymerizationNanoparticles

references

更多指标>

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Organocatalytic Polymerization of Sulfur-containing One-carbon Monomer and Epoxides

Dynamic and Rheological Behavior of Particle Crosslinked Vitrimers

Synthesis and Properties of Polystyrene-g-Poly(2-ethyl-2-oxazoline) Amphiphilic Graft Copolymers

Synthesis and Two-dimentional Self-assembly of Amphiphilic and Conjugated Polymers Based on Poly(phenylenebutadiynylene)s

Progress in Janus Composites toward Interfacial Engineering

Related Author

No data

Related Institution

MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University

Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

State Key Laboratory of Chemical Resources Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology

Key Laboratory of Soft Matter Chemistry, Chinese Academy of Sciences; Department of Polymer Science and Engineering, University of Science and Technology of China

State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences

Postal code：100190
Tel：010-62588927 Email：gfzxb@iccas.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05002797号-8 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰