Synthesis and Self-assembly of Hyperbranched Polymers

Qi Mei-wei; Huang Wei; Xiao Gu-yu; Zhu Xin-yuan; Gao Chao; Zhou Yong-feng

doi:10.11777/j.issn1000-3304.2017.16324

您当前的位置：

首页 >

文章列表页 >

Synthesis and Self-assembly of Hyperbranched Polymers

Reviews | 更新时间：2021-05-18

- Synthesis and Self-assembly of Hyperbranched Polymers
- Acta Polymerica Sinica Issue 2, Pages: 214-228(2017)
- 作者机构：
  
  1.上海交通大学化学化工学院上海 200240
  2.浙江大学高分子科学与工程系杭州 310027
- 作者简介：
- 基金信息：
- DOI：10.11777/j.issn1000-3304.2017.16324
  CLC：
- Published：20 February 2017，
  
  Received：26 October 2016，
  
  Revised：27 November 2016，
扫描看全文
Qi Mei-wei, Huang Wei, Xiao Gu-yu, Zhu Xin-yuan, Gao Chao, Zhou Yong-feng. Synthesis and Self-assembly of Hyperbranched Polymers. [J]. Acta Polymerica Sinica (2):214-228(2017)
DOI：

Qi Mei-wei, Huang Wei, Xiao Gu-yu, Zhu Xin-yuan, Gao Chao, Zhou Yong-feng. Synthesis and Self-assembly of Hyperbranched Polymers. [J]. Acta Polymerica Sinica (2):214-228(2017) DOI： 10.11777/j.issn1000-3304.2017.16324.

摘要

超支化聚合物作为树形聚合物的一种，具有独特的结构和性能，受到了科学界和工业界的广泛关注.本文简要总结了研究者们在超支化聚合物的合成、组装及应用方面的部分工作成果.主要包括以下3方面的内容：第一部分介绍了超支化聚合物的合成方法；第二部分介绍了超支化聚合物多维多尺度的自组装结构和组装机理，包括纳米球形胶束，纳米、微米级囊泡，大的复合囊泡，纳米纤维，纳米、微米及宏观管和多孔膜等；第三部分介绍了超支化聚合物在生物医药、细胞模拟及纳米粒子模拟制备等方面的应用.

Abstract

Hyperbranched polymers (HBPs)

comprising of dendritic units

linear units and terminal units

are highly branched macromolecules with three-dimensional dendritic globular architecture. Compared with linear polymers

HBPs have shown the characteristics of a large population of terminal functional groups

low or no chain entanglement

small hydrodynamic diameter

low solution or melt viscosity and good solubility. Due to these characteristics

HBPs have attracted global interest from science to industry. In this paper

we review some progress in the synthesis

self-assembly and application of HBPs. The paper includes three parts. In the first part

a short history on the development of HBPs focusing on the introduction of "couple-monomer methodology (CMM)" to prepare HBPs was discussed. A typical example of CMM named as "AA'+B'B

" method was described. In addition

the synthesis of a hyperbranched oxetanemethanol through ring-opening polymerization was also presented. In the second part

the self-assembly of amphiphilic HBPs was summarized according to the morphology of the self-assemblies from the spherical micelles

the vesicles

the sheets or films

the fibers or tubes

to complex supramolecular structures. The mechanism for the self-assembly of the micelles from HBPs was discussed in details. HBPs form unimolecular micelles (UMs) around 10 nm below the critical micellar concentration (CMC). Above the CMC

there are two possibilities for the formation of micelles:one is that HBPs undergo microphase separation and then form micelles with the diameter of the length of two HBPs (around 20 nm or larger)

which is named as "microphase-separated small micelles" (ms-SMs) and similar to the star micelles of linear block copolymers in structure; the other is that HBPs form multimolecular micelles (

50 nm) through a mechanism of "multimicelle aggregate" (MMA). The MMA mechanism can also be divided into two mechanisms of "unimolecular micelle aggregate" (UMA) and "small micelle aggregate" (SMA). The MAA mechanism is general and can also be used to explain the large multimolecular micelles self-assembled from other polymers or even small molecules. In the third part of this review

we introduced the applications of HBP self-assemblies in drug delivery

cytomimetic chemistry and monodisperse nanoparticle preparation. The HBP vesicles (named as branched-polymersomes) have displayed good properties like the simple preparation

good membrane fluidity and stability

and the facilely tuned and micrometer-scaled size

which make them the ideal model systems to mimic cell behaviors like fusion

fission

aggregation and so on. All these cytomimetic behaviors can be observed in real time under an optical microscope since the branched-polymersomes have a cell-like size.

关键词

超支化聚合物自组装药物传输胶束囊泡

Keywords

Hyperbranched polymersSelf-assemblyDrug deliveryMicellesVesicles

references

P J Flory . . J Am Chem Soc , 1952 . 74 ( 11 ): 2718 - 2723 . DOI:10.1021/ja01131a008http://doi.org/10.1021/ja01131a008.

Y H Kim , O W Webster . . Polym Prepr , 1988 . 29 ( 2 ): 310 - 311.

D Y Yan , C Gao . . Macromolecules , 2000 . 33 ( 21 ): 7693 - 76939 . DOI:10.1021/ma000438jhttp://doi.org/10.1021/ma000438j.

C Gao , D Y Yan . . Prog Polym Sci , 2004 . 29 ( 3 ): 183 - 275 . DOI:10.1016/j.progpolymsci.2003.12.002http://doi.org/10.1016/j.progpolymsci.2003.12.002.

P Froehling , J Brackman . . Macromol Symp , 2000 . 151 ( 1 ): 581 - 589 . DOI:10.1002/(ISSN)1521-3900http://doi.org/10.1002/(ISSN)1521-3900.

J M J Fréchet , M Henmi , I Gitsov , S Aoshima , M R Leduc , R B Grubbs . . Science , 1995 . 269 ( 5227 ): 1080 - 1083 . DOI:10.1126/science.269.5227.1080http://doi.org/10.1126/science.269.5227.1080.

J Han , S Li , A Tang , C Gao . . Macromolecules , 2012 . 45 ( 45 ): 4966 - 4977.

M Liu , N Vladimirov , J M J Fréchet . . Macromolecules , 1999 . 32 ( 20 ): 6881 - 6884 . DOI:10.1021/ma990785xhttp://doi.org/10.1021/ma990785x.

M Trollsås , P Löwenhielm , V Y Lee , M Möller , R D Miller , J L Hedrick . . Macromolecules , 1999 . 32 ( 26 ): 9062 - 9066 . DOI:10.1021/ma991039vhttp://doi.org/10.1021/ma991039v.

L Nuhn , C Schull , H Frey , R Zentel . . Macromolecules , 2013 . 46 ( 8 ): 2892 - 2904 . DOI:10.1021/ma4002897http://doi.org/10.1021/ma4002897.

H T Chang , J M Fréchet . . J Am ChemSoc , 1999 . 121 ( 10 ): 2313 - 2314 . DOI:10.1021/ja983797rhttp://doi.org/10.1021/ja983797r.

H Chen , Z Jia , D Y Yan , X Y Zhu . . Macromol Chem Phys , 2007 . 208 ( 15 ): 1637 - 1645 . DOI:10.1002/(ISSN)1521-3935http://doi.org/10.1002/(ISSN)1521-3935.

M Meldal , C W Tornøe . . Chem Rev , 2008 . 108 ( 8 ): 2952 - 3015 . DOI:10.1021/cr0783479http://doi.org/10.1021/cr0783479.

J Han , Y Zheng , S Zheng , S Li , T Hu , A Tang , C Gao . . Chem Commun , 2014 . 50 ( 63 ): 8712 - 8714 . DOI:10.1039/C4CC01956Chttp://doi.org/10.1039/C4CC01956C.

A Vander Ende , E J Kravitz , E Harth . . J Am Chem Soc , 2008 . 130 ( 27 ): 8706 - 8713 . DOI:10.1021/ja711417hhttp://doi.org/10.1021/ja711417h.

D A Tomalia , J M J Fréchet . . J Polym Sci, Part A:Polym Chem , 2002 . 40 ( 16 ): 2719 - 2728 . DOI:10.1002/pola.10301http://doi.org/10.1002/pola.10301.

X Y Zhu , Y F Zhou , D Y Yan . . J. Polym Sci, Part B:Polym Phys , 2011 . 49 ( 5 ): 1277 - 1286.

B I Voit , A Lederer . . Chem Rev , 2009 . 109 ( 11 ): 5924 - 5973 . DOI:10.1021/cr900068qhttp://doi.org/10.1021/cr900068q.

M Bednarek , T Biedron , J Helinski , K Kaluzynski , P Kubisa , S Penczek . . Macromol Rapid Commun , 1999 . 20 ( 7 ): 369 - 372 . DOI:10.1002/(ISSN)1521-3927http://doi.org/10.1002/(ISSN)1521-3927.

H Magnusson , E Malmström , A Hult . . Macromol Rapid Commun , 1999 . 20 ( 8 ): 453 - 457 . DOI:10.1002/(ISSN)1521-3927http://doi.org/10.1002/(ISSN)1521-3927.

D Y Yan , J Hou , X Y Zhu , J J Kosman , H S Wu . . Macromol Rapid Commun , 2000 . 21 ( 9 ): 557 - 561 . DOI:10.1002/(ISSN)1521-3927http://doi.org/10.1002/(ISSN)1521-3927.

D Y Yan , Y F Zhou , J Hou . . Science , 2004 . 303 ( 5654 ): 65 - 67 . DOI:10.1126/science.1090763http://doi.org/10.1126/science.1090763.

Y F Zhou , D Y Yan . . Chem Commun , 2009 . 10 ( 10 ): 1172 - 1188.

Y F Zhou , W Huang , J Y Liu , X Y Zhu , D Y Yan . . Adv Mater , 2010 . 22 ( 41 ): 4567 - 4590 . DOI:10.1002/adma.201000369http://doi.org/10.1002/adma.201000369.

X Y Zhu , Y F Zhou , D Y Yan . . J Polym Sci, Part B:Polym Phys , 2011 . 49 ( 18 ): 1277 - 1286 . DOI:10.1002/polb.22320http://doi.org/10.1002/polb.22320.

D L Wang , T Y Zhao , X Y Zhu , D Y Yan , W X Wang . . Chem Soc Rev , 2015 . 44 ( 12 ): 4023 - 4071 . DOI:10.1039/C4CS00229Fhttp://doi.org/10.1039/C4CS00229F.

J Y Liu , W Huang , Y Pang , D Y Yan . . Chem Soc Rev , 2015 . 44 ( 12 ): 3942 - 3953 . DOI:10.1039/C5CS00318Khttp://doi.org/10.1039/C5CS00318K.

H B Jin , W Huang , X Y Zhu , Y F Zhou , D Y Yan . . Chem Soc Rev , 2012 . 41 ( 41 ): 5986 - 5997.

W F Jiang , Y F Zhou , D Y Yan . . Chem Soc Rev , 2015 . 44 ( 12 ): 3874 - 3889 . DOI:10.1039/C4CS00274Ahttp://doi.org/10.1039/C4CS00274A.

YY Mai , Y F Zhou , D Y Yan . . Macromolecules , 2005 . 38 ( 21 ): 8679 - 8686 . DOI:10.1021/ma051377yhttp://doi.org/10.1021/ma051377y.

B Guo , X Y Sun , Y F Zhou , D Y Yan . . Sci China Chem , 2010 . 53 ( 3 ): 487 - 494 . DOI:10.1007/s11426-010-0083-2http://doi.org/10.1007/s11426-010-0083-2.

W Y Dong , Y F Zhou , D Y Yan , H Li , Y Liu . . Phys Chem Chem Phys , 2007 . 9 ( 10 ): 1255 - 1262 . DOI:10.1039/b615525chttp://doi.org/10.1039/b615525c.

X Y Sun , W Huang , Y Zhou , D Yan . . Phys Chem Chem Phys , 2010 . 12 ( 38 ): 11984 - 11953 . DOI:10.1039/c0cp00819bhttp://doi.org/10.1039/c0cp00819b.

C Gao , X Zheng . . Soft Matter , 2009 . 5 ( 23 ): 4788 - 4796 . DOI:10.1039/b909994hhttp://doi.org/10.1039/b909994h.

M Jiang , Y Wu , Y He , J Nie . . Polym Int , 2009 . 58 ( 1 ): 31 - 39 . DOI:10.1002/pi.v58:1http://doi.org/10.1002/pi.v58:1.

C Konotoyianni , Z Sideratou , T Theodossiou , L A Tziveleka , D Tsiourvas , C M Paleos . . Macromol Biosci , 2008 . 8 ( 9 ):871 - 881 . DOI:10.1002/mabi.v8:9http://doi.org/10.1002/mabi.v8:9.

M Prabaharan , J J Grailer , S Pilla , D A Steeber , S Gong . . Macromol Biosci , 2009 . 9 ( 5 ): 515 - 524 . DOI:10.1002/mabi.v9:5http://doi.org/10.1002/mabi.v9:5.

H Y Chen , G L Li , H R Chi , D L Wang , C L Tu , L J Pan , L J Zhu , F Qiu , F L Guo , X Y Zhu . . Bioconjugate Chem , 2012 . 23 ( 9 ): 1915 - 1924 . DOI:10.1021/bc3003088http://doi.org/10.1021/bc3003088.

D L Wang , H Y Chen , Y Su , F Qiu , L J Zhu , X Y Huan , B S Zhu , D Y Yan , F L Guo , X Y Zhu . . Polym Chem , 2013 . 4 ( 1 ): 85 - 94 . DOI:10.1039/C2PY20573Dhttp://doi.org/10.1039/C2PY20573D.

S J T Rezaei , H S Bandansari , M R Nabid , H J Niknejad . . Colloid Interface Sci , 2014 . 425 ( 425 ): 27 - 35.

S J Xu , Y Luo , R Haag . . Macromol Biosci , 2007 . 7 ( 8 ): 968 - 974.

M R Radowski , A Shukla , H Von Berlepsch , C Böttcher , G Pickaert , H Rehage , R Haag . . Angew Chem Int Ed , 2007 . 46 ( 8 ): 1265 - 1269 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

L A Tziveleka , C Kontoyianni , Z Sideratou , D Tsiourvas , C M Paleos . . Macromol Biosci , 2006 . 6 ( 2 ): 161 - 169 . DOI:10.1002/(ISSN)1616-5195http://doi.org/10.1002/(ISSN)1616-5195.

H X Cheng , S G Wang , J T Yang , Y F Zhou , D Y Yan . . J Colloid Interface Sci , 2009 . 337 ( 1 ): 278 - 284 . DOI:10.1016/j.jcis.2009.05.026http://doi.org/10.1016/j.jcis.2009.05.026.

Y F Zhang , J G Wang , L N Zhang . . Langmuir , 2010 . 26 ( 22 ): 17617 - 17623 . DOI:10.1021/la1033959http://doi.org/10.1021/la1033959.

L Q Yang , SS Fu , X N Zhu , L M Zhang , Y R Yang , X M Yang , H Liu . . Biomacromolecules , 2010 . 11 ( 12 ): 3395 - 3405 . DOI:10.1021/bm100902dhttp://doi.org/10.1021/bm100902d.

J Y Liu , W Huang , Y F Zhou , D Y Yan . . Macromolecules , 2009 . 42 ( 13 ): 4394 - 4399 . DOI:10.1021/ma900798hhttp://doi.org/10.1021/ma900798h.

J Y Liu , Y Pang , W Huang , X Zhai , X Y Zhu , Y F Zhou , D Y Yan . . Macromolecules , 2010 . 43 ( 20 ): 8416 - 8423 . DOI:10.1021/ma1015819http://doi.org/10.1021/ma1015819.

J Y Liu , W Huang , Y Pang , P Huang , X Y Zhu , Y F Zhou , D Y Yan . . Angew Chem Int Ed , 2011 . 50 ( 39 ): 9162 - 9166 . DOI:10.1002/anie.201102280http://doi.org/10.1002/anie.201102280.

J Y Liu , Y Pang , J Chen , P Huang , W Huang , X Y Zhu , D Y Yan . . Biomaterials , 2012 . 33 ( 31 ): 7765 - 7774 . DOI:10.1016/j.biomaterials.2012.07.003http://doi.org/10.1016/j.biomaterials.2012.07.003.

Zhilin Hou , Yongfeng Zhou , Deyue Yan . . Chin Polym Bull , 2015 . ( 9 ): 5 - 20 . http://www.cqvip.com/QK/95630X/201509/666148743.html.

侯志林 , 周永丰 , 颜德岳 . . 高分子通报 , 2015 . ( 9 ): 5 - 20 . http://www.cqvip.com/QK/95630X/201509/666148743.html.

H Y Hong , YY Mai , Y F Zhou , D Y Yan , J Cui . . Macromol Rapid Commun , 2007 . 28 ( 28 ): 591 - 596.

M Radowski , A Shukla , C Böttcher , G Pickaert , H Rehage , R Haag . . Angew Chem Int Ed , 2007 . 46 ( 8 ): 1265 - 1269 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

Y L Wang , B Li , Y F Zhou , Z Y Lu , D Y Yan . . Soft matter , 2013 . 9 ( 12 ): 3293 - 3304 . DOI:10.1039/c3sm27396bhttp://doi.org/10.1039/c3sm27396b.

X Y Sun , Y F Zhou , D Y Yan . . Macromol Chem Phys , 2010 . 211 ( 17 ): 1940 - 1946 . DOI:10.1002/macp.201000250http://doi.org/10.1002/macp.201000250.

Y N Liu , J Y Jin , H P Deng , K Li , Y L Zheng , C Y Yu , Y F Zhou . . Angew Chem Int Ed , 2016 . 55 ( 28 ): 8084 - 8089.

Y F Zhou , D Y Yan . . Angew Chem Int Ed , 2004 . 43 ( 37 ): 4896 - 4899 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

Y F Zhou , D Y Yan , W Y Dong , Y Tian . . J Phys Chem B , 2007 . 111 ( 6 ): 1262 - 1270 . DOI:10.1021/jp0673563http://doi.org/10.1021/jp0673563.

J H Zou , X D Ye , W F Shi . . Macromol Rapid Commun , 2005 . 26 ( 21 ): 1741 - 1745 . DOI:10.1002/(ISSN)1521-3927http://doi.org/10.1002/(ISSN)1521-3927.

Z Q Shi , Y F Zhou , D Y Yan . . Macromol Rapid Commun , 2008 . 29 ( 5 ): 412 - 418 . DOI:10.1002/(ISSN)1521-3927http://doi.org/10.1002/(ISSN)1521-3927.

B Guo , Z Q Shi , Y Yao , Y F Zhou , D Y Yan . . Langmuir , 2009 . 25 ( 12 ): 6622 - 6626 . DOI:10.1021/la901366ghttp://doi.org/10.1021/la901366g.

H X Cheng , S G Wang , J T Yang , Y F Zhou , D Y Yan . . J Colloid Interface Sci , 2009 . 337 ( 1 ): 278 - 284 . DOI:10.1016/j.jcis.2009.05.026http://doi.org/10.1016/j.jcis.2009.05.026.

Z P Guo , Y H Li , H Y Tian , X L Zhuang , X S Chen , X B Jing . . Langmuir , 2009 . 25 ( 17 ): 9690 - 9696 . DOI:10.1021/la900932jhttp://doi.org/10.1021/la900932j.

Y Liu , C Y Yu , H B Jin , B B Jiang , X Y Zhu , Y F Zhou , Z Y Lu , D Y Yan . . J Am Chem Soc , 2013 . 135 ( 12 ): 4765 - 4770 . DOI:10.1021/ja3122608http://doi.org/10.1021/ja3122608.

W Tao , Y Liu , BB Jiang , S R Yu , W Huang , Y F Zhou , D Y Yan . . J Am Chem Soc , 2012 . 134 ( 2 ): 762 - 764 . DOI:10.1021/ja207924whttp://doi.org/10.1021/ja207924w.

W F Jiang , Y Liu , C Y Yu , S L Li , Y J Li , Y Zhou . . Chem Commun , 2016 . 52 ( 53 ): 8223 - 8226 . DOI:10.1039/C6CC03445Dhttp://doi.org/10.1039/C6CC03445D.

D P Zhang , Y J Fan , H M Li , K Li , Y Yan , Y F Zhou , D Y Yan . . RSC Adv , 2015 . 5 ( 59 ): 47762 - 47765 . DOI:10.1039/C5RA08661Bhttp://doi.org/10.1039/C5RA08661B.

C H Liu , C Gao , D Yan . . Angew Chem Int Ed , 2007 . 46 ( 22 ): 4128 - 4131 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

W Dong , Y Zhou , D Yan , Y Mai , L He , C Jin . . Langmuir , 2009 . 25 ( 1 ): 173 - 178 . DOI:10.1021/la802863mhttp://doi.org/10.1021/la802863m.

J P Yeh , K K Rajesh , Y Q Zou , M Chiao , N K Jayachandran . . Langmuir , 2008 . 24 ( 9 ): 4907 - 4916 . DOI:10.1021/la702867thttp://doi.org/10.1021/la702867t.

X F Hu , J Ji . . Biomacromolecules , 2011 . 12 ( 12 ): 4264 - 4271 . DOI:10.1021/bm201137xhttp://doi.org/10.1021/bm201137x.

X F Hu , J Ji . . Langmuir , 2010 . 26 ( 4 ): 2624 - 2629 . DOI:10.1021/la902719khttp://doi.org/10.1021/la902719k.

G H Jiang , L Wang , T Chen , H J Yu , X C Dong , C Chen . . Polymer , 2005 . 46 ( 22 ): 9501 - 9507 . DOI:10.1016/j.polymer.2005.07.036http://doi.org/10.1016/j.polymer.2005.07.036.

D P Zhang , Y N Liu , Y J Fan , C Y Yu , Y L Zheng , H B Jin , L Fu , Y F Zhou , D Y Yan . . Adv Funct Mater , 2016 . 42 ( 26 ): 7652 - 7661.

I Böhm , K Isenbügel , H Ritter , R Branscheid , U Kolb . . Angew Chem Int Edit , 2011 . 123 ( 32 ): 7334 - 7334.

M Ornatska , S Peleshanko , K L Genson , B Rybak , K N Bergman , V V Tsukruk . . J Am Chem Soc , 2004 . 126 ( 31 ): 9675 - 9684 . DOI:10.1021/ja0498944http://doi.org/10.1021/ja0498944.

M Ornatska , K N Bergman , B Rybak , S Peleshanko , V V Tsukruk . . Angew Chem Int Ed , 2004 . 43 ( 39 ): 5246 - 5249 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

C Gao , X Zheng . . Soft Matter , 2009 . 5 ( 23 ): 4788 - 4796 . DOI:10.1039/b909994hhttp://doi.org/10.1039/b909994h.

J Mao , P H Ni , YY Mai , D Yan . . Langmuir , 2007 . 23 ( 9 ): 5127 - 5134 . DOI:10.1021/la063576whttp://doi.org/10.1021/la063576w.

YY Mai , Y F Zhou , D Y Yan . . Small , 2007 . 3 ( 7 ): 1170 - 1173 . DOI:10.1002/(ISSN)1613-6829http://doi.org/10.1002/(ISSN)1613-6829.

H B Jin , Y F Zhou , W Huang , D Y Yan . . Langmuir , 2010 . 26 ( 18 ): 14512 - 14519 . DOI:10.1021/la102963whttp://doi.org/10.1021/la102963w.

D Dunlap , A Maggi , M Soria , L Monaco . . Nucleic Acids Res , 1997 . 25 ( 15 ): 3095 - 3101 . DOI:10.1093/nar/25.15.3095http://doi.org/10.1093/nar/25.15.3095.

Q Zhu , F Qiu , B S Zhu , X Y Zhu . . RSC Advances , 2013 . 3 ( 7 ): 2071 - 2083 . DOI:10.1039/C2RA22210Hhttp://doi.org/10.1039/C2RA22210H.

S R Yu , R J Dong , J X Chen , W F Jiang , Y F Zhou , D Y Yan . . Biomacromolecules , 2014 . 15 ( 5 ): 1828 - 1836 . DOI:10.1021/bm5002203http://doi.org/10.1021/bm5002203.

F Wurm , J Klos , H Rader , H Frey . . J Am Chem Soc , 2009 . 131 ( 23 ): 7954 - 7955 . DOI:10.1021/ja9019148http://doi.org/10.1021/ja9019148.

C Kontoyianni , Z Sideratou , T Theodossiou , L Tziveleka , D Tsiourvas , C Paleos . . Macromo Biosci , 2008 . 8 ( 9 ): 871 - 881 . DOI:10.1002/mabi.v8:9http://doi.org/10.1002/mabi.v8:9.

L Tziveleka , C Kontoyianni , Z Sideratou , D Tsiourvas , C Paleos . . Macromol Biosci , 2006 . 6 ( 2 ): 161 - 169 . DOI:10.1002/(ISSN)1616-5195http://doi.org/10.1002/(ISSN)1616-5195.

Y F Zhou , X Y Sun , D Yan . . Sci China Ser B Chem , 2009 . 52 ( 10 ): 1703 - 1710 . DOI:10.1007/s11426-009-0227-4http://doi.org/10.1007/s11426-009-0227-4.

Y Pang , J Y Liu , J L Wu , G Li , R B Wang , Y Su , P He , X Y Zhu , D Y Yan , B S Zhu . . Bioconjugate Chem , 2010 . 21 ( 21 ): 2093 - 2102.

Y Huang , D L Wang , X Y Zhu , D Y Yan , R Chen . . Polym Chem , 2015 . 6 ( 15 ): 2794 - 2812 . DOI:10.1039/C5PY00144Ghttp://doi.org/10.1039/C5PY00144G.

Yan Li , Wei Huang , Ping Huang , Xinyuan Zhu , Deyue Yan . . Progress in Chemistry , 2014 . 26 ( 8 ): 1395 - 1408 . http://www.progchem.ac.cn/CN/abstract/abstract11408.shtml.

黎燕 , 黄卫 , 黄平 , 朱新远 , 颜德岳 . . 化学进展 , 2014 . 26 ( 8 ): 1395 - 1408 . http://www.progchem.ac.cn/CN/abstract/abstract11408.shtml.

Y F Zhou , D Y Yan . . J Am Chem Soc , 2005 . 127 ( 30 ): 10468 - 10469 . DOI:10.1021/ja0505696http://doi.org/10.1021/ja0505696.

Y F Zhou , D Y Yan . . Angew Chem Int Ed , 2005 . 44 ( 21 ): 3223 - 3226 . DOI:10.1002/(ISSN)1521-3773http://doi.org/10.1002/(ISSN)1521-3773.

H B Jin , Y L Zheng , Y Liu , H Cheng , Y F Zhou , D Y Yan . . Angew Chem Int Ed , 2011 . 123 ( 44 ): 10536 - 10540 . DOI:10.1002/ange.v123.44http://doi.org/10.1002/ange.v123.44.

H B Jin , Y Liu , Y L Zheng , W Huang , Y F Zhou , D Y Yan . . Langmuir , 2012 . 28 ( 4 ): 2066 - 2072 . DOI:10.1021/la203857shttp://doi.org/10.1021/la203857s.

H B Jin , Y F Zhou , Y Huang , Y L Zheng , X Y Zhu , D Y Yan . . Chem Commun , 2014 . 50 ( 46 ): 6157 - 6160 . DOI:10.1039/c4cc00609ghttp://doi.org/10.1039/c4cc00609g.

H B Jin , W Huang , Y L Zheng , Y F Zhou , D Y Yan . . Chem Eur J , 2012 . 18 ( 28 ): 8641 - 8646 . DOI:10.1002/chem.v18.28http://doi.org/10.1002/chem.v18.28.

T Huang , X H Huang , X Y Sun , Y F Zhou , Y P Bai , D Y Yan . . Chem Commun , 2014 . 50 ( 55 ): 7363 - 7366 . DOI:10.1039/c4cc02520bhttp://doi.org/10.1039/c4cc02520b.

T Huang , H M Li , L Huang , S L Li , K Li , Y F Zhou . . Langmuir , 2016 . 32 ( 4 ): 991 - 996 . DOI:10.1021/acs.langmuir.5b04478http://doi.org/10.1021/acs.langmuir.5b04478.

更多指标>

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Antibacterial Micelles Self-assembled from Copolypeptides through a One-step Acidification Process

Antibacterial Hydrogels Incoporated with Poly(glutamic acid)-based Vesicles

Preparation of Micelles and Gels via Polymerization of Pre-assembled Styrene and Polyacrylic Acid

Progress in Syntheses and Applications of Polypeptides and Polypeptide-based Copolymers by NCA Polymerization

Related Author

No data

Related Institution

Department of Orthopedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine

Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University

Key Laboratory of Advanced Civil Engineering Materials of the Ministry of Education, School of Material Science and Engineering, Tongji University

Shanghai Key Laboratory of Advance Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology

School of Materials Science and Engineering, Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education, Tongji University

Postal code：100190
Tel：010-62588927 Email：gfzxb@iccas.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05002797号-8 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰