Ting-ting Sun, Zhou-ting Jiang. DYNAMICS OF DIFFERENT HELICAL PROTEIN-LIKE CHAINS TRANSLOCATING THROUGH A CYLINDRICAL CHANNEL. [J]. Acta Polymerica Sinica (8):1058-1063(2013)
DOI:
Ting-ting Sun, Zhou-ting Jiang. DYNAMICS OF DIFFERENT HELICAL PROTEIN-LIKE CHAINS TRANSLOCATING THROUGH A CYLINDRICAL CHANNEL. [J]. Acta Polymerica Sinica (8):1058-1063(2013) DOI: 10.3724/SP.J.1105.2013.12370.
DYNAMICS OF DIFFERENT HELICAL PROTEIN-LIKE CHAINS TRANSLOCATING THROUGH A CYLINDRICAL CHANNEL
The dynamics of different helical protein-like chains translocating through a channel has been studied by Dynamical Monte Carlo (DMC) simulation.Translocation time
translocation probability
the number of monomers inside channel nin
shape factor and mean-square displacement of center of mass g are discussed.It is shown translocation time of protein-like chain with small helical energy is short
and changes little.However
for chains of large helical energy
the translocation time quickly increases when h becomes stronger.The results show that the translocation probability is smaller as the electric field becomes stronger.For different helical chains the translocation probability of h=0 is the largest
about 80%
smaller than that of SAW chain.But it suddently drops for h=-0.5.Then the translocation probability increases again as the helical energy becomes stronger.Furthermore
the curve of nin shows the translocation process of SAW chains is more steady than that of protein-like chains.The maximum value in the curves of suggests there exists the loosest conformation during translocation.Another discussion about the mean-square displacement of center of mass g shows that g of h=0 changes faster than others.It shows diffusion of h=0 is the fastest.It is also observed that the value g of h=-3.0 changes faster than that of h=-1.5.The discussion of shape factor and mean-sqare displacement can explain the different properties of different helical protein-like chains.All these studies will be useful for the complex translocation behaviors of macromolecules.
关键词
动态蒙特卡洛(DMC)类蛋白质分子螺旋结构
Keywords
Dynamical Monte Carlo (DMC)Protein-like chainHelical structure