By the technology of inverse suspension polymerization

theophylline template phenolic resin sorbent (TTPS) and nontemplate phenolic resin sorbent (NTPS) have been synthesized.Comparison of theophylline adsorption on TTPS and NTPS was made.The experimental results showed that the adsorption data fitted the Langmuir model

which implied the monomolecular layer sorption in these systems.Theophylline adsorption data matched Freundilich equation within the low concentration range

which meant the adsorption was preferential.By Scatchard analysis

it was found that TTPS showed specific binding sites.The dissociation constants and the maximum binding capacity were calculated to be Kd1=0129 mmol/L and Qmax1=138 mol/g for high affinity binding sites and Kd2=0433 mmol/L and Qmax2=184 mol/g for lower affinity binding sites

respectively.Moreover

it was found that the sorption rate data of theophylline adequately fitted a semiempirical rate equationn in initial period.It confirmed the particlediffusion control mechanism of the sorption process.When 200 mmol/L solution of theophylline at the rate of 3 BV/h flowed through TTPS columns

breakthrough point was 24th bed volume under dynamic condition.It was clear that with 1 mol/L hydrochloric acid at the rate of desorption 15 BV/h the removing of 972% of all the theophylline adsorbed on TTPS was observed at 4 bed volumes.The result showed that TTPS possessed excellent desorption performance.