CHEN Jing-Xiao, WANG Hui-Yuan, XU Xiao-Ding, CHEN Wei-Hai, ZHANG Xian-Zheng. PEPTIDES AND POLYPEPTIDES FOR GENE AND DRUG DELIVERY[J]. Acta Polymerica Sinica, 2011,(8):799-811.
CHEN Jing-Xiao, WANG Hui-Yuan, XU Xiao-Ding, CHEN Wei-Hai, ZHANG Xian-Zheng. PEPTIDES AND POLYPEPTIDES FOR GENE AND DRUG DELIVERY[J]. Acta Polymerica Sinica, 2011,(8):799-811. DOI: 10.3724/SP.J.1105.2011.11100.
Peptides and polypeptides have been widely used for gene and drug delivery due to their inherent bioactivity
biodegradability and well biocompatibility.Due to the specific bioactivity of peptides
peptide-based gene and drug delivery systems could achieve improved gene transfection efficiency
enhanced drug targeting property and reduced side-effect.This article reviews the recent progress in peptides and polypeptides as gene and drug carriers.The mechanism and characteristics of some bioactive peptides were also introduced.Finally
the prospect of bioactive peptides in cancer treatments was proposed.