Polymer vesicles or hollow spheres as macromolecular self-assemblies are of great importance in theoretical studies as well as broad applications

especially in medicine fields.In this article

discussions on different routes of preparation of polymer vesicles or hollow spheres were presented.The traditional preparation methods for the assemblies include self-assembly of block copolymers

shell crosslinking and core removal of copolymer micelles and synthesis on the templates.The methods via non-covalently connected micelles (NCCM)

as well as the one-step synthesis from monomers to polymer vesicles were reviewed in detail.These methods have overcome the laborious multistep processes including using a preorganized structure and subsequent removal of the core or templates et al.Recent progresses in functional block copolymer vesicles

such as the micelle-vesicle transition

breathing vesicles

bursting of sensitive polymersomes and surface modification of polymeric vesicles have been highlighted.