Polylactide containing phosphorylcholine (PLA-PC) and polylactide (PLA) were synthesized with lactide (LA) as monomer

glycerophosphorylcholine and 1

4-butanediol as ring-opening initiators respectively.The comparison investigation of inducing mineralization on PLA-PC and PLA films was conducted.The result demonstrated that mineralized products could form on the film of PLA-PC as well as on the film of PLA in the simulated body fluid (SBF) of pH 6.8. Moreover

formation of the mineralized products was easier on the film of PLA-PC than on the film of PLA.The reason for that is phosphorylcholines can migrate to the surfaces of polymers when PLA-PC contacts with water

and PLA-PC can combine with more Ca2+ than PLA because phosphoryl in PLA-PC can combine with Ca2+ owing to the interaction between negative charge and positive charge.Fourier-transform infrared (FTIR)

X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to characterize the mineralized products formed on the surface of PLA-PC films.The results showed that the mineral crystal was hydroxylapatite (HAP) and the crystal had a laminated structure.PLA-PC films are good for nucleation and development of crystals.The crystalline grains and crystalline thickness grew with increasing mineralization time.Therefore

PLA-PC is a promising biodegradable scaffolds material for bone tissue engineering.