A series of well-defined hydrophobic copolymers latexes of fluorinated acrylate (FA) with 2-methacrylatoethyl trimethyl ammonium chloride (DMC) were synthesized as potential colloidal templates

and then the core-shell FA copolymer SiO2 hybrid nanoparticles (NPs) with a mobile core were synthesized via deposition of tetramethyl orthosilicate (TMOS) in aqueous media at room temperature

allowing the formation of hollow-structured silica NPs by subsequent calcinations.No experimental evidence was found for nontemplated silica formation

which indicated that silica deposition occurred exclusively in the latex surface and formed FA copolymer-SiO2 hybrid NPs

which was confirmed by the combination of FTIR

EDX

TGA and XPS determination.Studies from TEM and TGA indicated that the morphology and composition of the resulted SiO2 hybrid nanoparticles could be well controlled by adjusting the DMC concentration

the amount of TMOS and the deposition time.Higher DMC concentration

higher level of TMOS amount or longer deposition time produced the FA copolymer-SiO2 hybrid nanoparticles with more enriched SiO2 content and thicker SiO2 shell.Moreover

the morphology of the core-shell hybrid nanoparticles with dented wrinkled surface turned to regular spherical nanoparticles with a mobile core after SiO2 deposition.These new core-shell FA copolymer-SiO2 hybrid nanoparticles with a mobile core and corresponding hollow-structured silica nanoparticles would have potential applications for high-performance encapsulation and delivery of drugs

pigments and the active organic molecules.