LI Ping, RONG Fei, ZHU Xinle, HU Junzhe, YUAN Chunwei. STUDIES ON THE PREPARATION OF L-2-CHLOROMANDELIC ACID-IMPRINTED POLYMER AND ITS SELECTIVE BINDING CHARACTERISTICS[J]. Acta Polymerica Sinica, 2003,(5):724-727.
LI Ping, RONG Fei, ZHU Xinle, HU Junzhe, YUAN Chunwei. STUDIES ON THE PREPARATION OF L-2-CHLOROMANDELIC ACID-IMPRINTED POLYMER AND ITS SELECTIVE BINDING CHARACTERISTICS[J]. Acta Polymerica Sinica, 2003,(5):724-727.DOI:
A molecularly imprinted polymer (MIP) was synthesized from the photoinduced polymerization of acrylamide and butylene diacrylate in the presence of L-2-chloromandelic acid (L-2-MDA) as template and was used as a highly selective separation materials for L-2-MDA.UV analysis showed the template L-2-MDA and functional monomer acrylamide formed complexes before polymerization.The structures of complexes were simulated by using Hyperchem and the binding energies were calculated as -1.6437×104 J·mol-1 and -4.2799×104 J·mol-1.The binding capacity of MIP to L-2-MDA was higher than that of other analogs and the chiral separation factor α was 1.76.Scatchard analysis suggested that the MIP recognized α-2-MDA with two classes of binding sites
which is accordant with the two kinds of complex simulation models.