The methyl-ester-terminated G1.5

2.5 and 3.5 poly(amidoamine) dendrimers (PAMAM) are hydrolyzed by using NaOH to obtain external carboxylate groups with them (PAMAMC)．These dendrimers show interaction with cytochrome C in some extent．For example

the reduction rate of FeⅢ-cytochrome C to FeⅡ-cytochrome C by asorbic acid was clearly slowed down because of the interaction between cytochrome C and PAMAM dendrimers．The reaction happened only betweem FeⅢ-eytochrome C and ascorbic acid

it showed a pseudofirst order constant of 3.48 min-1．When PAMAMC (G2.5 or 3.5) dendrimers were added in the reaction system

the pseudo-first order constant dropped to 1.40 or 1.32 min-1．The association constant of l:1 cytochrome C-G2.5C is 2.4×104 and the association constant of l:1 cytochrome C-G3.5C is 2.6×104．