Ce Shi, Yun-qi Li. Progress on the Application of Small-angle X-ray Scattering in the Study of Protein and Protein Complexes[J]. Acta Polymerica Sinica, 2015,(8):871-883.
Ce Shi, Yun-qi Li. Progress on the Application of Small-angle X-ray Scattering in the Study of Protein and Protein Complexes[J]. Acta Polymerica Sinica, 2015,(8):871-883. DOI: 10.11777/j.issn1000-3304.2015.15048.
Small angle X-ray scattering (SAXS) is a powerful technique to study the interaction and structure at spatial scale from several to hundreds nanometers.Structure-based drug design has vigorously promoted the application of SAXS in protein complex study.Physical principles
facilities
data collection and interpretations are concisely introduced.Then two cutting-edge topics of SAXS applications including protein conformation in solutions
and the interaction and structure in protein complexes
combined with routine information acquirement and tips in these cases have been reviewed.
关键词
小角X射线散射蛋白质复合物结构相互作用
Keywords
Small angle X-ray scatteringProtein complexStructureInteraction