DNA水凝胶的构建及柔性电子应用

李颀; 王丽华; 樊春海; 叶德楷

doi:10.11777/j.issn1000-3304.2023.23308

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DNA水凝胶的构建及柔性电子应用

综述 | 更新时间：2024-06-05

- DNA水凝胶的构建及柔性电子应用
- Construction of DNA Hydrogels and Flexible Electronic Applications
- 高分子学报 2024年55卷第6期页码：655-672
- 作者机构：
  
  1.中国科学院上海应用物理研究所中国科学院界面物理与技术重点实验室上海 201800
  2.中国科学院大学北京 100049
  3.张江实验室上海 201210
  4.上海交通大学化学化工学院上海 200240
- 作者简介：
  
  [ "叶德楷，男，1989年生. 2011年于南京大学生命科学学院获得学士学位；2019年于中国科学院上海应用物理研究所获得博士学位；2019~2022年，中国科学院化学研究所从事博士后研究. 2022年加入张江实验室，现任副研究员. 2022年获上海市启明星资助. 主要研究方向为框架核酸自组装器件构筑及功能应用." ]
- 基金信息：
  
  上海市启明星(22QA1411800)
- DOI：10.11777/j.issn1000-3304.2023.23308
  中图分类号：
- 纸质出版日期：2024-06-20，
  
  网络出版日期：2024-03-28，
  
  收稿日期：2023-12-31，
  
  录用日期：2024-02-02
- 稿件说明：
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李颀, 王丽华, 樊春海, 叶德楷. DNA水凝胶的构建及柔性电子应用. 高分子学报, 2024, 55(6), 655-672

Li, Q.; Wang, L. H.; Fan, C. M.; Ye, D. K. Construction of DNA hydrogels and flexible electronic applications. Acta Polymerica Sinica, 2024, 55(6), 655-672
李颀, 王丽华, 樊春海, 叶德楷. DNA水凝胶的构建及柔性电子应用. 高分子学报, 2024, 55(6), 655-672 DOI： 10.11777/j.issn1000-3304.2023.23308.

Li, Q.; Wang, L. H.; Fan, C. M.; Ye, D. K. Construction of DNA hydrogels and flexible electronic applications. Acta Polymerica Sinica, 2024, 55(6), 655-672 DOI： 10.11777/j.issn1000-3304.2023.23308.

摘要

水凝胶材料能有效提升柔性电子器件与人体组织的相容性，在智能穿戴、健康监测和人机接口等研究领域展现了巨大的应用潜力. 然而，传统的水凝胶材料难以在器件界面进行原位无损的结构调控，同时也缺乏对多类型生化刺激的识别响应能力，这制约了水凝胶柔性电子器件的高性能构筑和多功能应用. DNA水凝胶制备工艺温和，结构精确可控且具有丰富的生化识别响应性，是柔性电子器件功能化的理想材料之一. 本文着重介绍了DNA水凝胶的材料特性及其柔性电子器件应用的研究进展. 首先介绍了纯DNA水凝胶和杂化DNA水凝胶的制备方法，以及面向多类型功能界面的构筑策略. 通过对DNA水凝胶力学特性、识别响应性和生物相容性的深入分析，展示了其在器件功能调控和生物医学应用方面的重要价值. 其次，详细探讨了DNA水凝胶功能化的柔性电子器件在传感、储能和显示等方面的研究进展，展现了其在人体健康监测和智能穿戴领域的应用前景. 最后，对DNA水凝胶在柔性生物电子领域的未来发展进行了展望.

Abstract

Hydrogels serve as effective functional interface materials that enhance compatibility between human tissues and flexible electronic devices. These hydrogel-based devices exhibit great potential in research areas like smart wearables

health monitoring

and human-machine interfaces. However

traditional hydrogel materials pose challenges in achieving controllable fabrication at the device interface and designing responses to biological and chemical stimuli. These limitations restrain the creation of high-performance hydrogel-based flexible electronic devices for intelligent applications. This article primarily aims to introduce the distinctive material properties of novel DNA hydrogels and their advancements in flexible electronic devices. Initially

we introduced the fabrication techniques for both pure and hybrid DNA hydrogels

alongside strategies for regulating functional interfaces. Subsequently

an in-depth analysis of DNA hydrogels' mechanical properties

stimulus responsiveness

and biocompatibility is provided. Specifically

we explored how these crucial attributes can be harnessed in designing functional devices and biomedical applications. Moreover

we outlined the progress of DNA hydrogel-based flexible electronic devices in sensing

energy storage

and displaying. These advancements showcase their significant potential in human health monitoring and smart wearables. Finally

we discussed the prospective development directions of DNA hydrogels in the domain of flexible bioelectronics.

关键词

DNA水凝胶刺激响应柔性电子器件传感器

Keywords

DNA hydrogelStimulus-responseFlexible devicesSensor

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