用于压力传感的多孔皮革/羧基化碳纳米管复合材料及其在血压监测中的应用

潘宇江; 姚帝杰; 罗艺冰; 吴进

doi:10.11777/j.issn1000-3304.2026.26028

您当前的位置：

首页 >

文章列表页 >

用于压力传感的多孔皮革/羧基化碳纳米管复合材料及其在血压监测中的应用

研究论文 | 更新时间：2026-04-03

- 用于压力传感的多孔皮革/羧基化碳纳米管复合材料及其在血压监测中的应用
- Porous Leather/Carboxylated Carbon Nanotube Composites: Pressure Sensing and Blood Pressure Monitoring Applications
- 高分子学报 2026年页码：1-14
- 作者机构：
  
  中山大学光电材料与技术国家重点实验室电子与信息工程学院广州 510275
- 作者简介：
  
  E-mail: wujin8@mail.sysu.edu.cn
- 基金信息：
  
  国家自然科学基金(基金号 22475243);材料复合新技术全国重点实验室(武汉理工大学)开放基金(基金号 2025-KF-10)和广东大学生科技创新培育专项资金(pdjh2025ak004)
- DOI：10.11777/j.issn1000-3304.2026.26028
  中图分类号：
- CSTR：32057.14.GFZXB.2026.7567
- 收稿：2026-02-02，
  
  录用：2026-02-26，
  
  网络首发：2026-04-03，
- 稿件说明：
移动端阅览
潘宇江, 姚帝杰, 罗艺冰, 吴进. 用于压力传感的多孔皮革/羧基化碳纳米管复合材料及其在血压监测中的应用. 高分子学报, doi: 10.11777/j.issn1000-3304.2026.26028.

Pan, Y. J. ; Yao, D. J.; Luo, Y. B.; Wu, J. Porous leather/carboxylated carbon nanotube composites: pressure sensing and blood pressure monitoring applications. Acta Polymerica Sinica (in Chinese), doi: 10.11777/j.issn1000-3304.2026.26028.
潘宇江, 姚帝杰, 罗艺冰, 吴进. 用于压力传感的多孔皮革/羧基化碳纳米管复合材料及其在血压监测中的应用. 高分子学报, doi: 10.11777/j.issn1000-3304.2026.26028. DOI： CSTR： 32057.14.GFZXB.2026.7567.

Pan, Y. J. ; Yao, D. J.; Luo, Y. B.; Wu, J. Porous leather/carboxylated carbon nanotube composites: pressure sensing and blood pressure monitoring applications. Acta Polymerica Sinica (in Chinese), doi: 10.11777/j.issn1000-3304.2026.26028. DOI： CSTR： 32057.14.GFZXB.2026.7567.

摘要

柔性电子技术的发展推进了柔性传感器在人体健康监测和疾病远程诊疗领域的应用. 本研究利用高分子材料皮革内部具备多尺度孔隙的特点，制备出压力传感器，并与微控制器和神经网络算法结合，构建了一个实时、舒适、透气的血压监测系统. 所使用的基于皮革与羧基化碳纳米管复合材料的压力传感器具有高灵敏度(14.83 kPa

-1

)、快速响应(160 ms)和恢复时间(60 ms)以及低检测限(40 Pa). 除此之外，该传感器还继承了皮革本身柔性和透气的特点，使其能够在实现高质量传感的同时保证穿戴舒适性，尤其适用于脉搏检测的使用场景. 该传感器与微处理器和神经网络构建的智能监测系统能够实现人体脉搏信号的处理以及高准确度的实时血压预测，突破传统血压测量方法的瓶颈，在人体健康监测和疾病早期诊断领域展现出了巨大的应用潜力.

Abstract

The development of flexible electronic technology drives the application of flexible sensors in the fields of human health monitoring and remote diagnosis and treatment of diseases. In this study

a pressure sensor was fabricated by taking advantage of the inherent multi-scale pore structure in leather

a polymeric material. The sensor was then combined with a microcontroller and a neural network algorithm to construct a real-time

comfortable and breathable blood pressure monitoring system. The pressure sensor based on the leather/carboxylated carbon nanotube composite exhibited high sensitivity (14.83 kPa

-1

)

fast response (160 ms)

short recovery time (60 ms) and a low detection limit (40 Pa). In addition

this sensor inherited the intrinsic

flexibility and breathability of leather

which enabled it to ensure wearing comfort while achieving high-quality sensing performance

making it particularly suitable for pulse detection scenarios. The intelligent monitoring system constructed by integrating this sensor with a microprocessor and a neural network could process human pulse signals and realize high-accuracy real-time blood pressure prediction. It breaks through the bottlenecks of traditional blood pressure measurement methods and demonstrates great application potential in the fields of human health monitoring and early diagnosis of diseases.

关键词

Keywords

references

Ezzati M. ; Obermeyer Z. ; Tzoulaki I. ; Mayosi B. M. ; Elliott P. ; Leon D. A. Contributions of risk factors and medical care to cardiovascular mortality trends . Nat. Rev. Cardiol. , 2015 , 12 ( 9 ), 508 - 530 . doi: 10.1038/nrcardio.2015.82 http://dx.doi.org/10.1038/nrcardio.2015.82

Zhou B. ; Danaei G. ; Stevens G. A. ; Bixby H. ; Taddei C. ; Carrillo-Larco R. M. ; Solomon B. ; Riley L. M. ; Di Cesare M. ; Iurilli M. L. C. ; Rodriguez-Martinez A. ; Zhu A. ; Hajifathalian K. ; Amuzu A. ; Banegas J. R. ; Bennett J. E. ; Cameron C. ; Cho Y. ; Clarke J. ; Craig C. L. ; Cruz J. J. ; Gates L. ; Giampaoli S. ; Gregg E. W. ; Hardy R. ; Hayes A. J. ; Ikeda N. ; Jackson R. T. ; Jennings G. ; Joffres M. ; Khang Y. H. ; Koskinen S. ; Kuh D. ; Kujala U. M. ; Laatikainen T. ; Lehtimäki T. ; Lopez-Garcia E. ; Lundqvist A. ; Maggi S. ; Magliano D. J. ; Mann J. I. ; McLean R. M. ; McLean S. B. ; Miller J. C. ; Morgan K. ; Neuhauser H. K. ; Niiranen T. J. ; Noale M. ; Oh K. ; Palmieri L. ; Panza F. ; Parnell W. R. ; Peltonen M. ; Raitakari O. ; Rodríguez-Artalejo F. ; Roy J. G. ; Salomaa V. ; Sarganas G. ; Servais J. ; Shaw J. E. ; Shibuya K. ; Solfrizzi V. ; Stavreski B. ; Tan E. J. ; Turley M. L. ; Vanuzzo D. ; Viikari-Juntura E. ; Weerasekera D. ; Ezzati M. Long-term and recent trends in hypertension awareness , treatment, and control in 12 countrieshigh-income : an analysis of 123 nationally representative surveys . Lancet, 2019 , 394 ( 10199 ), 639 - 651 . doi: 10.1016/s0140-6736(19)31145-6 http://dx.doi.org/10.1016/s0140-6736(19)31145-6

Allen J. Photoplethysmography and its application in clinical physiological measurement . Physiol. Meas. , 2007 , 28 ( 3 ), R 1 . doi: 10.1088/0967-3334/28/3/r01 http://dx.doi.org/10.1088/0967-3334/28/3/r01

O'Rourke M. F. ; Pauca A. ; Jiang X. J. Pulse wave analysis . Br. J. Clin. Pharmacol. , 2001 , 51 ( 6 ), 507 - 522 . doi: 10.1046/j.0306-5251.2001.01400.x http://dx.doi.org/10.1046/j.0306-5251.2001.01400.x

Chowdhury A. H. ; Jafarizadeh B. ; Baboukani A. R. ; Pala N. ; Wang C. L. Monitoring and analysis of cardiovascular pulse waveforms using flexible capacitive and piezoresistive pressure sensors and machine learning perspective . Biosens. Bioelectron. , 2023 , 237 , 115449 . doi: 10.1016/j.bios.2023.115449 http://dx.doi.org/10.1016/j.bios.2023.115449

Ding Q. L. ; Wang H. ; Zhou Y. B. ; Zhang Z. C. ; Luo Y. B. ; Wu Z. X. ; Yang L. ; Xie R. J. ; Yang B. R. ; Tao K. ; Pan S. W. ; Liu F. ; Fu J. ; Huo F. W. ; Wu J. Self-powered switchable gas-humidity difunctional flexible chemosensors based on smart adaptable hydrogel . Adv. Mater. , 2025 , 37 ( 24 ), 2502369 . doi: 10.1002/adma.202502369 http://dx.doi.org/10.1002/adma.202502369

Lee S. ; Franklin S. ; Hassani F. A. ; Yokota T. ; Nayeem M. O. G. ; Wang Y. ; Leib R. ; Cheng G. ; Franklin D. W. ; Someya T. Nanomesh pressure sensor for monitoring finger manipulation without sensory interference . Science , 2020 , 370 ( 6519 ), 966 - 970 . doi: 10.1126/science.abc9735 http://dx.doi.org/10.1126/science.abc9735

Wang H. M. ; Zhang Y. ; Liang X. P. ; Zhang Y. Y. Smart fibers and textiles for personal health management . ACS Nano , 2021 , 15 ( 8 ), 12497 - 12508 . doi: 10.1021/acsnano.1c06230 http://dx.doi.org/10.1021/acsnano.1c06230

Li H. C. ; Ma Y. J. ; Liang Z. W. ; Wang Z. H. ; Cao Y. ; Xu Y. ; Zhou H. ; Lu B. W. ; Chen Y. ; Han Z. Y. ; Cai S. S. ; Feng X. Wearable skin-like optoelectronic systems with suppression of motion artifacts for cuff-less continuous blood pressure monitor . Natl. Sci. Rev. , 2020 , 7 ( 5 ), 849 - 862 . doi: 10.1093/nsr/nwaa022 http://dx.doi.org/10.1093/nsr/nwaa022

Wang L. Q. ; Tian S. ; Zhu R. A new method of continuous blood pressure monitoring using multichannel sensing signals on the wrist . Microsyst. Nanoeng. , 2023 , 9 , 117 . doi: 10.1038/s41378-023-00590-4 http://dx.doi.org/10.1038/s41378-023-00590-4

Wang H. ; Ding Q. L. ; Luo Y. B. ; Wu Z. X. ; Yu J. H. ; Chen H. Z. ; Zhou Y. B. ; Zhang H. ; Tao K. ; Chen X. L. ; Fu J. ; Wu J. High-performance hydrogel sensors enabled multimodal and accurate human-machine interaction system for active rehabilitation . Adv. Mater. , 2024 , 36 ( 11 ), 2309868 . doi: 10.1002/adma.202309868 http://dx.doi.org/10.1002/adma.202309868

Chen J. M. ; Zhang J. ; Hu J. L. ; Luo N. Q. ; Sun F. X. ; Venkatesan H. ; Zhao N. ; Zhang Y. T. Ultrafast-response/recovery flexible piezoresistive sensors with DNA-like double helix yarns for epidermal pulse monitoring . Adv. Mater. , 2022 , 34 ( 2 ), 2104313 . doi: 10.1002/adma.202104313 http://dx.doi.org/10.1002/adma.202104313

Zhao Y. L. ; Sun Q. X. ; Mei S. X. ; Gao L. B. ; Zhang X. K. ; Yang Z. K. ; Nan X. L. ; Zhang H. Y. ; Xue C. Y. ; Li J. Y. Wearable multichannel-active pressurized pulse sensing platform . Microsyst. Nanoeng. , 2024 , 10 , 77 . doi: 10.1038/s41378-024-00703-7 http://dx.doi.org/10.1038/s41378-024-00703-7

Li J. Y. ; Wang H. ; Luo Y. B. ; Zhou Z. J. ; Zhang H. ; Chen H. Z. ; Tao K. ; Liu C. ; Zeng L. X. ; Huo F. W. ; Wu J. Design of AI-enhanced and hardware-supported multimodal E-skin for environmental object recognition and wireless toxic gas alarm . Nano Micro Lett. , 2024 , 16 ( 1 ), 256 . doi: 10.1007/s40820-024-01466-6 http://dx.doi.org/10.1007/s40820-024-01466-6

Bai N. N. ; Wang L. ; Wang Q. ; Deng J. ; Wang Y. ; Lu P. ; Huang J. ; Li G. ; Zhang Y. ; Yang J. L. ; Xie K. W. ; Zhao X. H. ; Guo C. F. Graded intrafillable architecture-based iontronic pressure sensor with ultra-broad-range high sensitivity . Nat. Commun. , 2020 , 11 , 209 . doi: 10.1038/s41467-019-14054-9 http://dx.doi.org/10.1038/s41467-019-14054-9

Jian M. Q. ; Xia K. L. ; Wang Q. ; Yin Z. ; Wang H. M. ; Wang C. Y. ; Xie H. H. ; Zhang M. C. ; Zhang Y. Y. Flexible and highly sensitive pressure sensors based on bionic hierarchical structures . Adv. Funct. Mater. , 2017 , 27 ( 9 ), 1606066 . doi: 10.1002/adfm.201606066 http://dx.doi.org/10.1002/adfm.201606066

Yang J. ; Luo S. ; Zhou X. ; Li J. L. ; Fu J. T. ; Yang W. D. ; Wei D. P. Flexible, tunable, and ultrasensitive capacitive pressure sensor with microconformal graphene electrodes . ACS Appl. Mater. Interfaces , 2019 , 11 ( 16 ), 14997 - 15006 . doi: 10.1021/acsami.9b02049 http://dx.doi.org/10.1021/acsami.9b02049

Atalay O. ; Atalay A. ; Gafford J. ; Walsh C. A highly sensitive capacitive-based soft pressure sensor based on a conductive fabric and a microporous dielectric layer . Adv. Mater. Technol. , 2018 , 3 ( 1 ), 1700237 . doi: 10.1002/admt.201700237 http://dx.doi.org/10.1002/admt.201700237

Liu C. ; Huang X. ; Zhou J. F. ; Chen Z. R. ; Liao X. P. ; Wang X. L. ; Shi B. Lightweight and high-performance electromagnetic radiation shielding composites based on a surface coating of Cu@Ag nanoflakes on a leather matrix . J. Mater. Chem. C , 2016 , 4 ( 5 ), 914 - 920 . doi: 10.1039/C5TC02591E http://dx.doi.org/10.1039/C5TC02591E

Wang X. L. ; Liao X. P. ; Zhang W. H. ; Shi B. Bio-inspired fabrication of hierarchical Ni-Fe-P coated skin collagen fibers for high-performance microwave absorption . Phys. Chem. Chem. Phys. , 2015 , 17 ( 3 ), 2113 - 2120 . doi: 10.1039/c4cp03909b http://dx.doi.org/10.1039/c4cp03909b

Dong Z. Y. ; Liu H. ; Yang X. ; Fan J. C. ; Bi H. C. ; Wang C. L. ; Zhang Y. H. ; Luo C. ; Chen X. Q. ; Wu X. Facile fabrication of paper-based flexible thermoelectric generator . npj Flex. Electron. , 2021 , 5 , 6 . doi: 10.1038/s41528-021-00103-1 http://dx.doi.org/10.1038/s41528-021-00103-1

Zeng W. J. ; Li C. ; Feng Y. ; Zeng S. H. ; Fu B. X. ; Zhang X. L. Carboxylated multi-walled carbon nanotubes (MWCNTs-COOH)-intercalated graphene oxide membranes for highly efficient treatment of organic wastewater . J. Water Process. Eng. , 2021 , 40 , 101901 . doi: 10.1016/j.jwpe.2020.101901 http://dx.doi.org/10.1016/j.jwpe.2020.101901

Wang Y. J. ; Zhang X. N. ; Song Y. H. ; Zhao Y. P. ; Chen L. ; Su F. M. ; Li L. B. ; Wu Z. L. ; Zheng Q. Ultrastiff and tough supramolecular hydrogels with a dense and robust hydrogen bond network . Chem. Mater. , 2019 , 31 ( 4 ), 1430 - 1440 . doi: 10.1021/acs.chemmater.8b05262 http://dx.doi.org/10.1021/acs.chemmater.8b05262

Lee G. ; Son J. ; Kim D. ; Ko H. J. ; Lee S. G. ; Cho K. Crocodile-skin-inspired omnidirectionally stretchable pressure sensor . Small , 2022 , 18 ( 52 ), 2205643 . doi: 10.1002/smll.202205643 http://dx.doi.org/10.1002/smll.202205643

Song Y. ; Chen H. T. ; Su Z. M. ; Chen X. X. ; Miao L. M. ; Zhang J. X. ; Cheng X. L. ; Zhang H. X. Highly compressible integrated supercapacitor-piezoresistance-sensor system with CNT-PDMS sponge for health monitoring . Small , 2017 , 13 ( 39 ), 1702091 . doi: 10.1002/smll.201702091 http://dx.doi.org/10.1002/smll.201702091

Zeng M. Z. ; Ding J. ; Tian Y. ; Zhang Y. S. ; Liu X. Y. ; Chen Z. H. ; Sun J. ; Wu C. H. ; Yin H. B. ; Wei D. ; Fan H. S. Phase separation manipulated gradient conductivity for a high-precision flexible pressure sensor . Adv. Funct. Mater. , 2024 , 34 ( 52 ), 2411390 . doi: 10.1002/adfm.202411390 http://dx.doi.org/10.1002/adfm.202411390

Ge C. Y. ; Li R. Z. ; Zhou L. J. ; An X. Y. ; Duan Z. ; Chen J. T. ; Li Y. ; Zhang S. Y. ; Hu P. G. ; Wang Z. L. ; Zhang J. Dual-function tactile sensor with linear pressure and temperature perception at low degree of coupling . Adv. Intell. Syst. , 2023 , 5 ( 5 ), 2370019 . doi: 10.1002/aisy.202370019 http://dx.doi.org/10.1002/aisy.202370019

Zhao P. F. ; Zhang R. M. ; Tong Y. H. ; Zhao X. L. ; Tang Q. X. ; Liu Y. C. All-paper, all-organic, cuttable, and foldable pressure sensor with tuneable conductivity polypyrrole . Adv. Electron. Mater. , 2020 , 6 ( 8 ), 1901426 .

Song Z. Q. ; Li W. Y. ; Bao Y. ; Wang W. ; Liu Z. B. ; Han F. J. ; Han D. X. ; Niu L. Bioinspired microstructured pressure sensor based on a Janus graphene film for monitoring vital signs and cardiovascular assessment . Adv. Electron. Mater. , 2018 , 4 ( 11 ), 1800252 . doi: 10.1002/aelm.201800252 http://dx.doi.org/10.1002/aelm.201800252

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

腰带型人体微环境可视化监测系统柔性集成与可穿戴应用研究

氢键侧链修饰共轭聚合物骨架的自愈合发光弹性体的设计合成与性能研究

新型薄膜太阳电池器件：柔性设计与印刷制造

基于前端开环易位聚合的本征阻燃PDCPD的制备及性能研究

高耐热共聚酰胺PA56T的直接固相聚合及结构性能研究