The transport and conformation of macromolecules in micro-channels were studied by using the dissipative particle dynamics(DPD) and finite extensible non-linear elastic(FENE) bead spring chains model.The dynamic behavior of macromolecules with different numbers of beads and different chain lengths in three kinds of micro-channels

straight

quadrate contraction and sloping contraction micro-channels are comparatively analyzed.It is found that macromolecules are mainly concentrated in the middle of channels.Macromolecules located near solid walls are stretched better than those in the middle of channels

which are usually coiled.The shape of micro-channel can influence the conformation and transportation of macromolecules.Straight channels can well stretch the macromolecules.Quadrate contraction channels can have negative effects in stretching the macromolecules with possible circulation flow at the corner areas.While the behavior of sloping contraction channels is between that of the straight channels and quadrate contraction channels.It is also found that macromolecule chains do not influence the temperature distribution and evolution.Instead macromolecular chains have remarkable influences on the density and velocity distribution

while the distribution and conformation of the macromolecules are closely related to the shape and geometry of the micro channels.The macromolecules tend to drag the simple DPD particles

reducing their velocity

and leading to density fluctuations.The dragging effect is more important as the number of macromolecules or the length of the macromolecular chain increases.