An endothelial preferential PTFE was developed via polydopamineassisted self\|assembly monolayer(SAM) technique.XPS

ellipsometer

QCMD and contact angle data confirmed the selfpolymerization process of DOPA and subsequently selfassembly monolayer formation of CGREDVDY.In cell adhesion experiments

both endothelial cells （ECs） and smooth muscle cells （SMCs） exhibited improved attachment on DOPA modified PTFE surfaces

but the surfaces did not have noticeable preference between the two cell types.However

after further SAM formation

those surfaces containing bioactive peptides CGREDVDY showed significant selection toward ECs.ECs preferential surface based on such approaches might open another window towards in situ endothelialization in those complex physiological environments in vivo.